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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015]
| Target ID |
GM-SE1299
|
| Target Name |
SOD3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6649
|
| Gene ID |
100146988 (Equus caballus), 111560198 (Felis catus), 20657 (Mus musculus), 25352 (Rattus norvegicus) 488855 (Canis lupus familiaris), 532481 (Bos taurus), 6649 (Homo sapiens), 715931 (Macaca mulatta)
|
| Target Alternative Names |
EC-SOD,ECSOD,ECSODPT,Extracellular superoxide dismutase [Cu-Zn],SOD3,Sod3
|
| Uniprot Accession |
O09164,Q08420,P08294
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Ovary Cancer, IgA glomerulonephritis
|
| Gene Ensembl |
ENSECAG00000035543, ENSMUSG00000072941, ENSCAFG00845007800, ENSBTAG00000013980, ENSG00000109610, ENSMMUG00000002612
|
Pre-made viral vector of SOD3 cDNA Clones/ORF Plasmid
SOD3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6649 | Pre-made Human SOD3/EC-SOD siRNA oligo Duplex | 6649 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25352 | Pre-made Rat Sod3/ECSODPT siRNA oligo Duplex | 25352 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20657 | Pre-made Mouse Sod3/EC-SOD siRNA oligo Duplex | 20657 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715931 | Pre-made Cynomolgus/Rhesus macaque SOD3 siRNA oligo Duplex | 715931 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111560198 | Pre-made Cat/Feline SOD3 siRNA oligo Duplex | 111560198 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488855 | Pre-made Dog/Canine SOD3 siRNA oligo Duplex | 488855 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532481 | Pre-made Bovines/Cattle SOD3/ECSOD/EC-SOD siRNA oligo Duplex | 532481 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146988 | Pre-made Equine/Horse SOD3 siRNA oligo Duplex | 100146988 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SOD3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1299-Ab | Human | Anti-Human SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1299-Ab | Rat | Anti-Rat SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1299-Ab | Mouse | Anti-Mouse SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1299-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1299-Ab | Cat/Feline | Anti-Cat/Feline SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1299-Ab | Dog/Canine | Anti-Dog/Canine SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1299-Ab | Bovines/Cattle | Anti-Bovines/Cattle SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1299-Ab | Equine/Horse | Anti-Equine/Horse SOD3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SOD3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1299-Ag | Human | Human SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1299-Ag | Rat | Rat SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1299-Ag | Mouse | Mouse SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1299-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1299-Ag | Cat/Feline | Cat/Feline SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1299-Ag | Dog/Canine | Dog/Canine SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1299-Ag | Bovines/Cattle | Bovines/Cattle SOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1299-Ag | Equine/Horse | Equine/Horse SOD3 recombinant protein | Mammalian cell | Detail |