Explore RSPO2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
| Target ID |
GM-SE1254
|
| Target Name |
RSPO2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
340419
|
| Gene ID |
100056523 (Equus caballus), 101087380 (Felis catus), 239405 (Mus musculus), 340419 (Homo sapiens)
482004 (Canis lupus familiaris), 500863 (Rattus norvegicus), 536121 (Bos taurus), 697376 (Macaca mulatta)
|
| Target Alternative Names |
2610028F08Rik,CRISTIN2,D430027K22,HHRRD,R-spondin-2,RGD1562331,RSPO2,Roof plate-specific spondin-2 (hRspo2),Rspo2,TETAMS2,ftls
|
| Uniprot Accession |
Q8BFU0,Q6UXX9
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000024853, ENSMUSG00000051920, ENSG00000147655, ENSBTAG00000013598, ENSMMUG00000054660
|
Pre-made viral vector of RSPO2 cDNA Clones/ORF Plasmid
RSPO2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo340419 | Pre-made Human RSPO2/HHRRD/TETAMS2 siRNA oligo Duplex | 340419 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500863 | Pre-made Rat Rspo2/RGD1562331 siRNA oligo Duplex | 500863 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo239405 | Pre-made Mouse Rspo2/ftls/D430027K22 siRNA oligo Duplex | 239405 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697376 | Pre-made Cynomolgus/Rhesus macaque RSPO2 siRNA oligo Duplex | 697376 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087380 | Pre-made Cat/Feline RSPO2 siRNA oligo Duplex | 101087380 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482004 | Pre-made Dog/Canine RSPO2 siRNA oligo Duplex | 482004 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536121 | Pre-made Bovines/Cattle RSPO2 siRNA oligo Duplex | 536121 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056523 | Pre-made Equine/Horse RSPO2 siRNA oligo Duplex | 100056523 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RSPO2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1254-Ab | Human | Anti-Human RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1254-Ab | Rat | Anti-Rat RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1254-Ab | Mouse | Anti-Mouse RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1254-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1254-Ab | Cat/Feline | Anti-Cat/Feline RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1254-Ab | Dog/Canine | Anti-Dog/Canine RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1254-Ab | Bovines/Cattle | Anti-Bovines/Cattle RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1254-Ab | Equine/Horse | Anti-Equine/Horse RSPO2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
RSPO2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1254-Ag | Human | Human RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1254-Ag | Rat | Rat RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1254-Ag | Mouse | Mouse RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1254-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1254-Ag | Cat/Feline | Cat/Feline RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1254-Ag | Dog/Canine | Dog/Canine RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1254-Ag | Bovines/Cattle | Bovines/Cattle RSPO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1254-Ag | Equine/Horse | Equine/Horse RSPO2 recombinant protein | Mammalian cell | Detail |
