Explore persephin/PSPN gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016]
| Target ID |
GM-SE1228
|
| Target Name |
persephin/PSPN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5623
|
| Gene ID |
100065517 (Equus caballus), 101085955 (Felis catus), 19197 (Mus musculus), 25525 (Rattus norvegicus)
518266 (Bos taurus), 5623 (Homo sapiens), 611734 (Canis lupus familiaris), 699480 (Macaca mulatta)
|
| Target Alternative Names |
PSP,PSPN,Persephin,Pspn,persephin
|
| Uniprot Accession |
O70300,O70301,O60542
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Gene Ensembl |
ENSMUSG00000002664, ENSG00000125650, ENSCAFG00845011239
|
persephin/PSPN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5623 | Pre-made Human PSPN/PSP siRNA oligo Duplex | 5623 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25525 | Pre-made Rat Pspn/PSP siRNA oligo Duplex | 25525 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19197 | Pre-made Mouse Pspn/PSP siRNA oligo Duplex | 19197 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699480 | Pre-made Cynomolgus/Rhesus macaque PSPN siRNA oligo Duplex | 699480 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085955 | Pre-made Cat/Feline PSPN siRNA oligo Duplex | 101085955 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611734 | Pre-made Dog/Canine PSPN siRNA oligo Duplex | 611734 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo518266 | Pre-made Bovines/Cattle PSPN siRNA oligo Duplex | 518266 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065517 | Pre-made Equine/Horse PSPN siRNA oligo Duplex | 100065517 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
persephin/PSPN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1228-Ab | Human | Anti-Human persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE1228-Ab | Rat | Anti-Rat persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE1228-Ab | Mouse | Anti-Mouse persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1228-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE1228-Ab | Cat/Feline | Anti-Cat/Feline persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE1228-Ab | Dog/Canine | Anti-Dog/Canine persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE1228-Ab | Bovines/Cattle | Anti-Bovines/Cattle persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE1228-Ab | Equine/Horse | Anti-Equine/Horse persephin/PSPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
persephin/PSPN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1228-Ag | Human | Human persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1228-Ag | Rat | Rat persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1228-Ag | Mouse | Mouse persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1228-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1228-Ag | Cat/Feline | Cat/Feline persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1228-Ag | Dog/Canine | Dog/Canine persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1228-Ag | Bovines/Cattle | Bovines/Cattle persephin/PSPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1228-Ag | Equine/Horse | Equine/Horse persephin/PSPN recombinant protein | Mammalian cell | Detail |
