Explore PDGFRL gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE1177
|
| Target Name |
PDGFRL
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5157
|
| Gene ID |
100050306 (Equus caballus), 101083001 (Felis catus), 290771 (Rattus norvegicus), 515017 (Bos taurus) 5157 (Homo sapiens), 607033 (Canis lupus familiaris), 68797 (Mus musculus), 703117 (Macaca mulatta)
|
| Target Alternative Names |
1110039P19Rik,PDGF receptor beta-like tumor suppressor,PDGFR-like protein,PDGFRL,PDGRL,PRLTS,Pdgfrl,Platelet-derived growth factor receptor-like protein
|
| Uniprot Accession |
Q5RJP7,Q5BIP2,Q15198,Q6PE55
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000021604, ENSBTAG00000001966, ENSG00000104213, ENSCAFG00845014856, ENSMUSG00000031595, ENSMMUG00000001153
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of PDGFRL cDNA Clones/ORF Plasmid
PDGFRL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5157 | Pre-made Human PDGFRL/PDGRL/PRLTS siRNA oligo Duplex | 5157 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo290771 | Pre-made Rat Pdgfrl siRNA oligo Duplex | 290771 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo68797 | Pre-made Mouse Pdgfrl/1110039P19Rik siRNA oligo Duplex | 68797 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703117 | Pre-made Cynomolgus/Rhesus macaque PDGFRL siRNA oligo Duplex | 703117 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083001 | Pre-made Cat/Feline PDGFRL siRNA oligo Duplex | 101083001 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607033 | Pre-made Dog/Canine PDGFRL siRNA oligo Duplex | 607033 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515017 | Pre-made Bovines/Cattle PDGFRL siRNA oligo Duplex | 515017 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050306 | Pre-made Equine/Horse PDGFRL siRNA oligo Duplex | 100050306 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDGFRL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1177-Ab | Human | Anti-Human PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE1177-Ab | Rat | Anti-Rat PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE1177-Ab | Mouse | Anti-Mouse PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1177-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE1177-Ab | Cat/Feline | Anti-Cat/Feline PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE1177-Ab | Dog/Canine | Anti-Dog/Canine PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE1177-Ab | Bovines/Cattle | Anti-Bovines/Cattle PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE1177-Ab | Equine/Horse | Anti-Equine/Horse PDGFRL monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
PDGFRL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1177-Ag | Human | Human PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1177-Ag | Rat | Rat PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1177-Ag | Mouse | Mouse PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1177-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1177-Ag | Cat/Feline | Cat/Feline PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1177-Ag | Dog/Canine | Dog/Canine PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1177-Ag | Bovines/Cattle | Bovines/Cattle PDGFRL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1177-Ag | Equine/Horse | Equine/Horse PDGFRL recombinant protein | Mammalian cell | Detail |