Explore IL-36 Beta/IL-1F8/IL36B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE1030
|
| Target Name |
IL-36 Beta/IL-1F8/IL36B
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
27177
|
| Gene ID |
100065096 (Equus caballus), 100297786 (Bos taurus), 27177 (Homo sapiens), 362076 (Rattus norvegicus) 483068 (Canis lupus familiaris), 69677 (Mus musculus), 701300 (Macaca mulatta)
|
| Target Alternative Names |
2310043N20Rik,FIL1,FIL1 eta,FIL1-(ETA),FIL1H,FILI-(ETA),IL-1F8,IL-1H2,IL-36 Beta,IL1-ETA,IL1F8,IL1H2,IL36B,If36b,Il1f8,Il36b,Interleukin-1 eta (IL-1 eta),Interleukin-1 family member 8 (IL-1F8),Interleukin-1 homolog 2 (IL-1H2),Interleukin-36 beta
|
| Uniprot Accession |
Q9NZH7,Q9D6Z6
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSBTAG00000059479, ENSG00000136696, ENSCAFG00845011786, ENSMUSG00000026985, ENSMMUG00000064457
|
Pre-made viral vector of IL-36 Beta/IL-1F8/IL36B cDNA Clones/ORF Plasmid
IL-36 Beta/IL-1F8/IL36B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27177 | Pre-made Human IL36B/FIL1/FIL1H siRNA oligo Duplex | 27177 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362076 | Pre-made Rat Il36b/Il1f8 siRNA oligo Duplex | 362076 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo69677 | Pre-made Mouse Il36b/If36b/Il1f8 siRNA oligo Duplex | 69677 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701300 | Pre-made Cynomolgus/Rhesus macaque IL36B/IL1F8 siRNA oligo Duplex | 701300 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483068 | Pre-made Dog/Canine IL36B/IL1F8 siRNA oligo Duplex | 483068 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100297786 | Pre-made Bovines/Cattle IL36B siRNA oligo Duplex | 100297786 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065096 | Pre-made Equine/Horse IL36B siRNA oligo Duplex | 100065096 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-36 Beta/IL-1F8/IL36B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1030-Ab | Human | Anti-Human IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE1030-Ab | Rat | Anti-Rat IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE1030-Ab | Mouse | Anti-Mouse IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1030-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE1030-Ab | Dog/Canine | Anti-Dog/Canine IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE1030-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE1030-Ab | Equine/Horse | Anti-Equine/Horse IL-36 Beta/IL-1F8/IL36B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-36 Beta/IL-1F8/IL36B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1030-Ag | Human | Human IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1030-Ag | Rat | Rat IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1030-Ag | Mouse | Mouse IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1030-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1030-Ag | Dog/Canine | Dog/Canine IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1030-Ag | Bovines/Cattle | Bovines/Cattle IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1030-Ag | Equine/Horse | Equine/Horse IL-36 Beta/IL-1F8/IL36B recombinant protein | Mammalian cell | Detail |