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Target
sublocation: Secreted Protein/Potential Cytokines.
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including B cell activation; lymphocyte activation involved in immune response; and positive regulation of peptidyl-serine phosphorylation of STAT protein. Predicted to act upstream of or within defense response to virus. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-SE0985
|
| Target Name |
IFNA8
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3445
|
| Gene ID |
3445 (Homo sapiens), 709755 (Macaca mulatta)
|
| Target Alternative Names |
IFN-alpha-8,IFN-alphaB,IFNA8,Interferon alpha-8,Interferon alpha-B (LeIF B),Interferon alpha-B2
|
| Uniprot Accession |
P32881
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Alcoholic liver disease, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Autoimmune thyroid disease, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSG00000120242, ENSMMUG00000063809
|
IFNA8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3445 | Pre-made Human IFNA8/IFN-alphaB siRNA oligo Duplex | 3445 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709755 | Pre-made Cynomolgus/Rhesus macaque IFNA8 siRNA oligo Duplex | 709755 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
IFNA8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0985-Ab | Human | Anti-Human IFNA8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0985-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IFNA8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IFNA8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0985-Ag | Human | Human IFNA8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0985-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IFNA8 recombinant protein | Mammalian cell | Detail |