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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. Expression of this gene has been observed in embryos and olfactory epithelium; however, the exact function of this gene is not known. This isozyme is a selenoprotein in humans, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The orthologs of this gene in mouse and rat (and some other species) contain a cysteine (Cys) residue in place of the Sec residue, and their corresponding mRNAs lack SECIS element. [provided by RefSeq, Jul 2017]
Target ID |
GM-SE0957
|
Target Name |
GPX6
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
257202
|
Gene ID |
100061078 (Equus caballus), 100286832 (Macaca mulatta), 101087577 (Felis catus), 257202 (Homo sapiens) 259233 (Rattus norvegicus), 488328 (Canis lupus familiaris), 519280 (Bos taurus), 75512 (Mus musculus)
|
Target Alternative Names |
GPX6,Gpx6,GPX5p,GPXP3,GPx-6,GSHPx-6,dJ1186N24,dJ1186N24.1,OBPII,Ry2d1,olfactory,1700020G18Rik
|
Uniprot Accession |
P59796,Q64625,Q91WR8
|
Uniprot Entry Name |
|
Protein Sub-location |
Secreted Protein/Potential Cytokines
|
Category |
|
Disease |
|
Disease from KEGG |
Metabolic pathways, Thyroid hormone synthesis, Arachidonic acid metabolism
|
Gene Ensembl |
ENSMMUG00000004617, ENSG00000198704, ENSCAFG00845017348, ENSMUSG00000004341
|
Target Classification |
|
GPX6 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo257202 | Pre-made Human GPX6/GPX5p/GPXP3 siRNA oligo Duplex | 257202 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo259233 | Pre-made Rat Gpx6/OBPII/Ry2d1 siRNA oligo Duplex | 259233 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo75512 | Pre-made Mouse Gpx6/Ry2d1/olfactory siRNA oligo Duplex | 75512 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo100286832 | Pre-made Cynomolgus/Rhesus macaque GPX6 siRNA oligo Duplex | 100286832 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101087577 | Pre-made Cat/Feline GPX6 siRNA oligo Duplex | 101087577 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo488328 | Pre-made Dog/Canine GPX6 siRNA oligo Duplex | 488328 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo519280 | Pre-made Bovines/Cattle GPX6 siRNA oligo Duplex | 519280 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100061078 | Pre-made Equine/Horse GPX6 siRNA oligo Duplex | 100061078 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GPX6 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-SE0957-Ab | Human | Anti-Human GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-rg-SE0957-Ab | Rat | Anti-Rat GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-mg-SE0957-Ab | Mouse | Anti-Mouse GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cynog-SE0957-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-felg-SE0957-Ab | Cat/Feline | Anti-Cat/Feline GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cang-SE0957-Ab | Dog/Canine | Anti-Dog/Canine GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-bovg-SE0957-Ab | Bovines/Cattle | Anti-Bovines/Cattle GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-equg-SE0957-Ab | Equine/Horse | Anti-Equine/Horse GPX6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GPX6 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-SE0957-Ag | Human | Human GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-SE0957-Ag | Rat | Rat GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-SE0957-Ag | Mouse | Mouse GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-SE0957-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-SE0957-Ag | Cat/Feline | Cat/Feline GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-SE0957-Ag | Dog/Canine | Dog/Canine GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-SE0957-Ag | Bovines/Cattle | Bovines/Cattle GPX6 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-SE0957-Ag | Equine/Horse | Equine/Horse GPX6 recombinant protein | Mammalian cell | Detail |