Explore GDF7 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
| Target ID |
GM-SE0942
|
| Target Name |
GDF7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
151449
|
| Gene ID |
100147101 (Equus caballus), 102152821 (Canis lupus familiaris), 111559870 (Felis catus), 151449 (Homo sapiens)
238057 (Mus musculus), 252833 (Rattus norvegicus), 286859 (Bos taurus), 702462 (Macaca mulatta)
|
| Target Alternative Names |
BMP12,GDF-7,GDF7,Gdf7,Growth/differentiation factor 7
|
| Uniprot Accession |
Q7Z4P5,P43029
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Axon guidance, Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000021083, ENSG00000143869, ENSMUSG00000037660, ENSBTAG00000038224
|
GDF7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo151449 | Pre-made Human GDF7/BMP12 siRNA oligo Duplex | 151449 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo252833 | Pre-made Rat Gdf7 siRNA oligo Duplex | 252833 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo238057 | Pre-made Mouse Gdf7/BMP12 siRNA oligo Duplex | 238057 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702462 | Pre-made Cynomolgus/Rhesus macaque GDF7 siRNA oligo Duplex | 702462 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111559870 | Pre-made Cat/Feline GDF7 siRNA oligo Duplex | 111559870 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102152821 | Pre-made Dog/Canine GDF7 siRNA oligo Duplex | 102152821 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286859 | Pre-made Bovines/Cattle GDF7 siRNA oligo Duplex | 286859 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147101 | Pre-made Equine/Horse GDF7 siRNA oligo Duplex | 100147101 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GDF7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0942-Ab | Human | Anti-Human GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0942-Ab | Rat | Anti-Rat GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0942-Ab | Mouse | Anti-Mouse GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0942-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0942-Ab | Cat/Feline | Anti-Cat/Feline GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0942-Ab | Dog/Canine | Anti-Dog/Canine GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0942-Ab | Bovines/Cattle | Anti-Bovines/Cattle GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0942-Ab | Equine/Horse | Anti-Equine/Horse GDF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GDF7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0942-Ag | Human | Human GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0942-Ag | Rat | Rat GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0942-Ag | Mouse | Mouse GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0942-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0942-Ag | Cat/Feline | Cat/Feline GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0942-Ag | Dog/Canine | Dog/Canine GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0942-Ag | Bovines/Cattle | Bovines/Cattle GDF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0942-Ag | Equine/Horse | Equine/Horse GDF7 recombinant protein | Mammalian cell | Detail |
