Explore GDF6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016]
| Target ID |
GM-SE0941
|
| Target Name |
GDF6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
392255
|
| Gene ID |
100059475 (Equus caballus), 111558542 (Felis catus), 119866692 (Canis lupus familiaris), 242316 (Mus musculus)
252834 (Rattus norvegicus), 392255 (Homo sapiens), 407175 (Bos taurus), 701126 (Macaca mulatta)
|
| Target Alternative Names |
BMP-13,BMP13,Bone morphogenetic protein 13 (BMP-13),CDMP-2,CDMP2,GDF-6,GDF16,GDF6,Gdf6,Growth/differentiation factor 16,Growth/differentiation factor 6,KFM,KFS,KFS1,KFSL,SGM1,SYNS4,gdf16
|
| Uniprot Accession |
P43028,Q6HA10,Q6KF10,P55106
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000006902, ENSCAFG00845016606, ENSMUSG00000051279, ENSG00000156466, ENSBTAG00000007687, ENSMMUG00000065198
|
GDF6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo392255 | Pre-made Human GDF6/KFM/KFS siRNA oligo Duplex | 392255 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo252834 | Pre-made Rat Gdf6/gdf16/BMP-13 siRNA oligo Duplex | 252834 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo242316 | Pre-made Mouse Gdf6/BMP13/GDF16 siRNA oligo Duplex | 242316 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701126 | Pre-made Cynomolgus/Rhesus macaque GDF6 siRNA oligo Duplex | 701126 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111558542 | Pre-made Cat/Feline GDF6 siRNA oligo Duplex | 111558542 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119866692 | Pre-made Dog/Canine GDF6 siRNA oligo Duplex | 119866692 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407175 | Pre-made Bovines/Cattle GDF6/BMP-13/CDMP-2 siRNA oligo Duplex | 407175 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059475 | Pre-made Equine/Horse GDF6 siRNA oligo Duplex | 100059475 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GDF6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0941-Ab | Human | Anti-Human GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0941-Ab | Rat | Anti-Rat GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0941-Ab | Mouse | Anti-Mouse GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0941-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0941-Ab | Cat/Feline | Anti-Cat/Feline GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0941-Ab | Dog/Canine | Anti-Dog/Canine GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0941-Ab | Bovines/Cattle | Anti-Bovines/Cattle GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0941-Ab | Equine/Horse | Anti-Equine/Horse GDF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GDF6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0941-Ag | Human | Human GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0941-Ag | Rat | Rat GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0941-Ag | Mouse | Mouse GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0941-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0941-Ag | Cat/Feline | Cat/Feline GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0941-Ag | Dog/Canine | Dog/Canine GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0941-Ag | Bovines/Cattle | Bovines/Cattle GDF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0941-Ag | Equine/Horse | Equine/Horse GDF6 recombinant protein | Mammalian cell | Detail |
