Explore GDF3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]
| Target ID |
GM-SE0940
|
| Target Name |
GDF3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9573
|
| Gene ID |
100061071 (Equus caballus), 101097251 (Felis catus), 14562 (Mus musculus), 477702 (Canis lupus familiaris)
500311 (Rattus norvegicus), 715605 (Macaca mulatta), 786521 (Bos taurus), 9573 (Homo sapiens)
|
| Target Alternative Names |
GDF3,Gdf3,Vgr2,Gdf-3,Vgr-2,ecat9,RGD1564178,KFS3,MCOP7,MCOPCB6
|
| Uniprot Accession |
Q07104,Q9NR23
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000017031, ENSMUSG00000030117, ENSCAFG00845029730, ENSMMUG00000052679, ENSBTAG00000023192, ENSG00000184344
|
| Target Classification |
|
GDF3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9573 | Pre-made Human GDF3/KFS3/MCOP7 siRNA oligo Duplex | 9573 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500311 | Pre-made Rat Gdf3/RGD1564178 siRNA oligo Duplex | 500311 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14562 | Pre-made Mouse Gdf3/Vgr2/Gdf-3 siRNA oligo Duplex | 14562 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715605 | Pre-made Cynomolgus/Rhesus macaque GDF3 siRNA oligo Duplex | 715605 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097251 | Pre-made Cat/Feline GDF3 siRNA oligo Duplex | 101097251 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477702 | Pre-made Dog/Canine GDF3 siRNA oligo Duplex | 477702 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo786521 | Pre-made Bovines/Cattle GDF3 siRNA oligo Duplex | 786521 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061071 | Pre-made Equine/Horse GDF3 siRNA oligo Duplex | 100061071 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GDF3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0940-Ab | Human | Anti-Human GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0940-Ab | Rat | Anti-Rat GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0940-Ab | Mouse | Anti-Mouse GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0940-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0940-Ab | Cat/Feline | Anti-Cat/Feline GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0940-Ab | Dog/Canine | Anti-Dog/Canine GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0940-Ab | Bovines/Cattle | Anti-Bovines/Cattle GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0940-Ab | Equine/Horse | Anti-Equine/Horse GDF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GDF3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0940-Ag | Human | Human GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0940-Ag | Rat | Rat GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0940-Ag | Mouse | Mouse GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0940-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0940-Ag | Cat/Feline | Cat/Feline GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0940-Ag | Dog/Canine | Dog/Canine GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0940-Ag | Bovines/Cattle | Bovines/Cattle GDF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0940-Ag | Equine/Horse | Equine/Horse GDF3 recombinant protein | Mammalian cell | Detail |
