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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0922
|
| Target Name |
FGF5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2250
|
| Gene ID |
100060219 (Equus caballus), 100136904 (Felis catus), 14176 (Mus musculus), 2250 (Homo sapiens) 536771 (Bos taurus), 60662 (Rattus norvegicus), 608459 (Canis lupus familiaris), 695896 (Macaca mulatta)
|
| Target Alternative Names |
FGF-5,FGF3A,FGF5,Fgf-5,Fgf3a,Fgf5,Fibroblast growth factor 5,HBGF-5,Heparin-binding growth factor 5 (HBGF-5),Smag-82,TCMGLY,angora,go
|
| Uniprot Accession |
M3X9S6,P15656,P12034,A0MTF4,P48807,Q20FD0
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Chemical carcinogenesis - receptor activation, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000015710, ENSMUSG00000029337, ENSG00000138675, ENSCAFG00845017837, ENSMMUG00000009067
|
Pre-made viral vector of FGF5 cDNA Clones/ORF Plasmid
FGF5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2250 | Pre-made Human FGF5/HBGF-5/TCMGLY siRNA oligo Duplex | 2250 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60662 | Pre-made Rat Fgf5/FGF-5/Fgf3a siRNA oligo Duplex | 60662 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14176 | Pre-made Mouse Fgf5/go/Fgf-5 siRNA oligo Duplex | 14176 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695896 | Pre-made Cynomolgus/Rhesus macaque FGF5 siRNA oligo Duplex | 695896 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100136904 | Pre-made Cat/Feline FGF5/FGF-5 siRNA oligo Duplex | 100136904 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608459 | Pre-made Dog/Canine FGF5 siRNA oligo Duplex | 608459 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536771 | Pre-made Bovines/Cattle FGF5/FGF-5/FGF3A siRNA oligo Duplex | 536771 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060219 | Pre-made Equine/Horse FGF5/FGF3A siRNA oligo Duplex | 100060219 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0922-Ab | Human | Anti-Human FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0922-Ab | Rat | Anti-Rat FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0922-Ab | Mouse | Anti-Mouse FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0922-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0922-Ab | Cat/Feline | Anti-Cat/Feline FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0922-Ab | Dog/Canine | Anti-Dog/Canine FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0922-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0922-Ab | Equine/Horse | Anti-Equine/Horse FGF5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
FGF5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0922-Ag | Human | Human FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0922-Ag | Rat | Rat FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0922-Ag | Mouse | Mouse FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0922-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0922-Ag | Cat/Feline | Cat/Feline FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0922-Ag | Dog/Canine | Dog/Canine FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0922-Ag | Bovines/Cattle | Bovines/Cattle FGF5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0922-Ag | Equine/Horse | Equine/Horse FGF5 recombinant protein | Mammalian cell | Detail |