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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
| Target ID |
GM-SE0763
|
| Target Name |
CFHR1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3078
|
| Gene ID |
3078 (Homo sapiens)
|
| Target Alternative Names |
CFHL,CFHL1,CFHL1P,CFHR1,CFHR1P,Complement factor H-related protein 1,FHL-1,FHR-1,FHR1,H factor-like protein 1 (FHL-1,H-factor-like 1),H36,H36-1,H36-2,HFL1,HFL2
|
| Uniprot Accession |
Q03591
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Complement and coagulation cascades
|
| Gene Ensembl |
ENSG00000244414
|
Pre-made viral vector of CFHR1 cDNA Clones/ORF Plasmid
CFHR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3078 | Pre-made Human CFHR1/H36/CFHL siRNA oligo Duplex | 3078 | Human | In-vitro grade; in-vivo grade | Detail |
CFHR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0763-Ab | Human | Anti-Human CFHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CFHR1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0763-Ag | Human | Human CFHR1 recombinant protein | Mammalian cell | Detail |