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Target
sublocation: Secreted Protein/Potential Cytokines.
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
| Target ID |
GM-SE0743
|
| Target Name |
CCL18/MIP-4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6362
|
| Gene ID |
574181 (Macaca mulatta), 6362 (Homo sapiens)
|
| Target Alternative Names |
AMAC-1,AMAC1,Alternative macrophage activation-associated CC chemokine 1 (AMAC-1),C-C motif chemokine 18,CC chemokine PARC,CCL18,CKb7,DC-CK1,DCCK1,Dendritic cell chemokine 1 (DC-CK1),MIP-4,Macrophage inflammatory protein 4 (MIP-4),PARC,Pulmonary and activation-regulated chemokine,SCYA18,Small-inducible cytokine A18
|
| Uniprot Accession |
Q8HYP8,P55774
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Prostate Cancer, Malignant neoplasm of bladder, Overactive bladder
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSMMUG00000047114, ENSG00000275385
|
Pre-made viral vector of CCL18/MIP-4 cDNA Clones/ORF Plasmid
CCL18/MIP-4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6362 | Pre-made Human CCL18/CKb7/PARC siRNA oligo Duplex | 6362 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574181 | Pre-made Cynomolgus/Rhesus macaque CCL18 siRNA oligo Duplex | 574181 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CCL18/MIP-4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0743-Ab | Human | Anti-Human CCL18/MIP-4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0743-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCL18/MIP-4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
CCL18/MIP-4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0743-Ag | Human | Human CCL18/MIP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0743-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCL18/MIP-4 recombinant protein | Mammalian cell | Detail |
