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Target
sublocation: Secreted Protein/Potential Cytokines.
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]
| Target ID |
GM-SE0739
|
| Target Name |
CCL13
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6357
|
| Gene ID |
100033951 (Equus caballus), 6357 (Homo sapiens), 714907 (Macaca mulatta)
|
| Target Alternative Names |
C-C motif chemokine 13,CCL13,CK-beta-10,CKb10,MCP-4,Monocyte chemoattractant protein 4,Monocyte chemotactic protein 4 (MCP-4),NCC-1,NCC1,SCYA13,SCYL1,Small-inducible cytokine A13
|
| Uniprot Accession |
Q99616
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Breast Cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, NF-kappa B signaling pathway
|
| Gene Ensembl |
ENSG00000181374, ENSMMUG00000009785
|
Pre-made viral vector of CCL13 cDNA Clones/ORF Plasmid
CCL13 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6357 | Pre-made Human CCL13/NCC1/CKb10 siRNA oligo Duplex | 6357 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714907 | Pre-made Cynomolgus/Rhesus macaque CCL13 siRNA oligo Duplex | 714907 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033951 | Pre-made Equine/Horse CCL13/MCP-4 siRNA oligo Duplex | 100033951 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CCL13 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0739-Ab | Human | Anti-Human CCL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0739-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0739-Ab | Equine/Horse | Anti-Equine/Horse CCL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
CCL13 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0739-Ag | Human | Human CCL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0739-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0739-Ag | Equine/Horse | Equine/Horse CCL13 recombinant protein | Mammalian cell | Detail |