Explore BMP8A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
| Target ID |
GM-SE0687
|
| Target Name |
BMP8A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
353500
|
| Gene ID |
100068680 (Equus caballus), 101089375 (Felis catus), 12163 (Mus musculus), 353500 (Homo sapiens)
680931 (Rattus norvegicus)
|
| Target Alternative Names |
BMP-8A,BMP8A,Bmp7r1,Bmp8a,Bone morphogenetic protein 8A,OP-2,OP2,Op2
|
| Uniprot Accession |
P34821,Q7Z5Y6
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000010065, ENSMUSG00000032726, ENSG00000183682
|
BMP8A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo353500 | Pre-made Human BMP8A/Op2/OP-2 siRNA oligo Duplex | 353500 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo680931 | Pre-made Rat Bmp8a siRNA oligo Duplex | 680931 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12163 | Pre-made Mouse Bmp8a/OP2/OP-2 siRNA oligo Duplex | 12163 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089375 | Pre-made Cat/Feline BMP8A siRNA oligo Duplex | 101089375 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068680 | Pre-made Equine/Horse BMP8A siRNA oligo Duplex | 100068680 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMP8A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0687-Ab | Human | Anti-Human BMP8A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0687-Ab | Rat | Anti-Rat BMP8A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0687-Ab | Mouse | Anti-Mouse BMP8A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0687-Ab | Cat/Feline | Anti-Cat/Feline BMP8A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0687-Ab | Equine/Horse | Anti-Equine/Horse BMP8A monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
BMP8A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0687-Ag | Human | Human BMP8A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0687-Ag | Rat | Rat BMP8A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0687-Ag | Mouse | Mouse BMP8A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0687-Ag | Cat/Feline | Cat/Feline BMP8A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0687-Ag | Equine/Horse | Equine/Horse BMP8A recombinant protein | Mammalian cell | Detail |
