Explore BMP5 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016]
| Target ID |
GM-SE0686
|
| Target Name |
BMP5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
653
|
| Gene ID |
100056806 (Equus caballus), 101097318 (Felis catus), 12160 (Mus musculus), 315824 (Rattus norvegicus) 474944 (Canis lupus familiaris), 507682 (Bos taurus), 653 (Homo sapiens), 711989 (Macaca mulatta)
|
| Target Alternative Names |
BMP-5,BMP5,Bmp5,Bone morphogenetic protein 5,se
|
| Uniprot Accession |
P49003,P22003
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000007138, ENSMUSG00000032179, ENSCAFG00845011840, ENSBTAG00000012870, ENSG00000112175, ENSMMUG00000011858
|
Pre-made viral vector of BMP5 cDNA Clones/ORF Plasmid
BMP5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo653 | Pre-made Human BMP5 siRNA oligo Duplex | 653 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo315824 | Pre-made Rat Bmp5 siRNA oligo Duplex | 315824 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12160 | Pre-made Mouse Bmp5/se siRNA oligo Duplex | 12160 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711989 | Pre-made Cynomolgus/Rhesus macaque BMP5 siRNA oligo Duplex | 711989 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097318 | Pre-made Cat/Feline BMP5 siRNA oligo Duplex | 101097318 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474944 | Pre-made Dog/Canine BMP5 siRNA oligo Duplex | 474944 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507682 | Pre-made Bovines/Cattle BMP5 siRNA oligo Duplex | 507682 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056806 | Pre-made Equine/Horse BMP5 siRNA oligo Duplex | 100056806 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMP5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0686-Ab | Human | Anti-Human BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0686-Ab | Rat | Anti-Rat BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0686-Ab | Mouse | Anti-Mouse BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0686-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0686-Ab | Cat/Feline | Anti-Cat/Feline BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0686-Ab | Dog/Canine | Anti-Dog/Canine BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0686-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0686-Ab | Equine/Horse | Anti-Equine/Horse BMP5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
BMP5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0686-Ag | Human | Human BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0686-Ag | Rat | Rat BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0686-Ag | Mouse | Mouse BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0686-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0686-Ag | Cat/Feline | Cat/Feline BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0686-Ag | Dog/Canine | Dog/Canine BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0686-Ag | Bovines/Cattle | Bovines/Cattle BMP5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0686-Ag | Equine/Horse | Equine/Horse BMP5 recombinant protein | Mammalian cell | Detail |