Explore BMP3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]
| Target ID |
GM-SE0685
|
| Target Name |
BMP3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
651
|
| Gene ID |
100060322 (Equus caballus), 100855862 (Canis lupus familiaris), 101093182 (Felis catus), 110075 (Mus musculus)
25667 (Rattus norvegicus), 539527 (Bos taurus), 651 (Homo sapiens), 695432 (Macaca mulatta)
|
| Target Alternative Names |
9530029I04Rik,BMP-3,BMP-3A,BMP3,Bmp3,Bone morphogenetic protein 3,Bone morphogenetic protein 3A (BMP-3A),Osteogenin,PBMP3
|
| Uniprot Accession |
Q8BHE5,P49002,P22444,P12645
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Colorectal Cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000014379, ENSCAFG00845017996, ENSMUSG00000029335, ENSBTAG00000017642, ENSG00000152785, ENSMMUG00000010347
|
Pre-made viral vector of BMP3 cDNA Clones/ORF Plasmid
BMP3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo651 | Pre-made Human BMP3/BMP-3A siRNA oligo Duplex | 651 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25667 | Pre-made Rat Bmp3/PBMP3 siRNA oligo Duplex | 25667 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110075 | Pre-made Mouse Bmp3/9530029I04Rik siRNA oligo Duplex | 110075 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695432 | Pre-made Cynomolgus/Rhesus macaque BMP3 siRNA oligo Duplex | 695432 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093182 | Pre-made Cat/Feline BMP3 siRNA oligo Duplex | 101093182 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855862 | Pre-made Dog/Canine BMP3 siRNA oligo Duplex | 100855862 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539527 | Pre-made Bovines/Cattle BMP3/BMP-3 siRNA oligo Duplex | 539527 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060322 | Pre-made Equine/Horse BMP3 siRNA oligo Duplex | 100060322 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMP3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0685-Ab | Human | Anti-Human BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0685-Ab | Rat | Anti-Rat BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0685-Ab | Mouse | Anti-Mouse BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0685-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0685-Ab | Cat/Feline | Anti-Cat/Feline BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0685-Ab | Dog/Canine | Anti-Dog/Canine BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0685-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0685-Ab | Equine/Horse | Anti-Equine/Horse BMP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
BMP3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0685-Ag | Human | Human BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0685-Ag | Rat | Rat BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0685-Ag | Mouse | Mouse BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0685-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0685-Ag | Cat/Feline | Cat/Feline BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0685-Ag | Dog/Canine | Dog/Canine BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0685-Ag | Bovines/Cattle | Bovines/Cattle BMP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0685-Ag | Equine/Horse | Equine/Horse BMP3 recombinant protein | Mammalian cell | Detail |
