Explore GDF11 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]
| Target ID |
GM-SE0629
|
| Target Name |
GDF11
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10220
|
| Gene ID |
100058832 (Equus caballus), 101090704 (Felis catus), 10220 (Homo sapiens), 14561 (Mus musculus)
29454 (Rattus norvegicus), 540517 (Bos taurus), 606826 (Canis lupus familiaris), 707708 (Macaca mulatta)
|
| Target Alternative Names |
BMP-11,BMP11,Bmp11,Bone morphogenetic protein 11 (BMP-11),GDF-11,GDF11,Gdf11,Growth/differentiation factor 11,VHO
|
| Uniprot Accession |
O95390,Q9Z1W4,Q9Z217
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000020505, ENSG00000135414, ENSMUSG00000025352, ENSBTAG00000007417, ENSCAFG00845005484, ENSMMUG00000006288
|
Pre-made viral vector of GDF11 cDNA Clones/ORF Plasmid
GDF11 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10220 | Pre-made Human GDF11/VHO/BMP11 siRNA oligo Duplex | 10220 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29454 | Pre-made Rat Gdf11/BMP-11 siRNA oligo Duplex | 29454 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14561 | Pre-made Mouse Gdf11/Bmp11/BMP-11 siRNA oligo Duplex | 14561 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707708 | Pre-made Cynomolgus/Rhesus macaque GDF11 siRNA oligo Duplex | 707708 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090704 | Pre-made Cat/Feline GDF11 siRNA oligo Duplex | 101090704 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo606826 | Pre-made Dog/Canine GDF11 siRNA oligo Duplex | 606826 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540517 | Pre-made Bovines/Cattle GDF11 siRNA oligo Duplex | 540517 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058832 | Pre-made Equine/Horse GDF11 siRNA oligo Duplex | 100058832 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GDF11 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0629-Ab | Human | Anti-Human GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0629-Ab | Rat | Anti-Rat GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0629-Ab | Mouse | Anti-Mouse GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0629-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0629-Ab | Cat/Feline | Anti-Cat/Feline GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0629-Ab | Dog/Canine | Anti-Dog/Canine GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0629-Ab | Bovines/Cattle | Anti-Bovines/Cattle GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0629-Ab | Equine/Horse | Anti-Equine/Horse GDF11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
GDF11 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0629-Ag | Human | Human GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0629-Ag | Rat | Rat GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0629-Ag | Mouse | Mouse GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0629-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0629-Ag | Cat/Feline | Cat/Feline GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0629-Ag | Dog/Canine | Dog/Canine GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0629-Ag | Bovines/Cattle | Bovines/Cattle GDF11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0629-Ag | Equine/Horse | Equine/Horse GDF11 recombinant protein | Mammalian cell | Detail |
