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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]
| Target ID |
GM-SE0602
|
| Target Name |
Pentraxin 3/PTX3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5806
|
| Gene ID |
100685178 (Canis lupus familiaris), 102149686 (Equus caballus), 102902276 (Felis catus), 19288 (Mus musculus) 541148 (Bos taurus), 5806 (Homo sapiens), 689388 (Rattus norvegicus), 704985 (Macaca mulatta)
|
| Target Alternative Names |
PTX3,Pentaxin-related protein PTX3,Pentraxin 3,Pentraxin-related protein PTX3,Ptx3,TNFAIP5,TSG-14,Tumor necrosis factor alpha-induced protein 5 (TNF alpha-induced protein 5),Tumor necrosis factor-inducible gene 14 protein (TSG-14)
|
| Uniprot Accession |
P48759,Q0VCG9,P26022
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Lung Cancer, Sepsis, Henoch-Schonlein Purpura Nephritis
|
| Gene Ensembl |
ENSCAFG00845024115, ENSECAG00000038866, ENSMUSG00000027832, ENSBTAG00000009012, ENSG00000163661, ENSMMUG00000062582
|
Pre-made viral vector of Pentraxin 3/PTX3 cDNA Clones/ORF Plasmid
Pentraxin 3/PTX3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5806 | Pre-made Human PTX3/TSG-14/TNFAIP5 siRNA oligo Duplex | 5806 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo689388 | Pre-made Rat Ptx3 siRNA oligo Duplex | 689388 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19288 | Pre-made Mouse Ptx3/TSG-14 siRNA oligo Duplex | 19288 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704985 | Pre-made Cynomolgus/Rhesus macaque PTX3 siRNA oligo Duplex | 704985 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102902276 | Pre-made Cat/Feline PTX3 siRNA oligo Duplex | 102902276 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100685178 | Pre-made Dog/Canine PTX3 siRNA oligo Duplex | 100685178 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541148 | Pre-made Bovines/Cattle PTX3 siRNA oligo Duplex | 541148 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149686 | Pre-made Equine/Horse PTX3 siRNA oligo Duplex | 102149686 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Pentraxin 3/PTX3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0602-Ab | Human | Anti-Human Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0602-Ab | Rat | Anti-Rat Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0602-Ab | Mouse | Anti-Mouse Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0602-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0602-Ab | Cat/Feline | Anti-Cat/Feline Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0602-Ab | Dog/Canine | Anti-Dog/Canine Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0602-Ab | Bovines/Cattle | Anti-Bovines/Cattle Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0602-Ab | Equine/Horse | Anti-Equine/Horse Pentraxin 3/PTX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
Pentraxin 3/PTX3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0602-Ag | Human | Human Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0602-Ag | Rat | Rat Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0602-Ag | Mouse | Mouse Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0602-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0602-Ag | Cat/Feline | Cat/Feline Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0602-Ag | Dog/Canine | Dog/Canine Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0602-Ag | Bovines/Cattle | Bovines/Cattle Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0602-Ag | Equine/Horse | Equine/Horse Pentraxin 3/PTX3 recombinant protein | Mammalian cell | Detail |