VTN/Vitronectin Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore VTN/Vitronectin gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene functions in part as an adhesive glycoprotein. Differential expression of this protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. This secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. This protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. This protein can also promote extracellular matrix degradation and thus plays a role in tumorigenesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of this protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein. [provided by RefSeq, Aug 2020]

Target ID GM-SE0548
Target Name VTN/Vitronectin
Gene Group ldentifer
(Target Gene ID in Homo species)
7448
Gene ID 100059034 (Equus caballus), 101100765 (Felis catus), 22370 (Mus musculus), 29169 (Rattus norvegicus)
480621 (Canis lupus familiaris), 507525 (Bos taurus), 708499 (Macaca mulatta), 7448 (Homo sapiens)
Target Alternative Names Aa1018,S-protein,Serum-spreading factor,V75,VN,VNT,VTN,Vitronectin,Vn,Vtn
Uniprot Accession P29788,P04004
Protein Sub-location Secreted Protein/Potential Cytokines
Disease from KEGG PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Complement and coagulation cascades, Human papillomavirus infection, Proteoglycans in cancer
Gene Ensembl ENSECAG00000015904, ENSMUSG00000017344, ENSCAFG00845007195, ENSBTAG00000016151, ENSMMUG00000019148, ENSG00000109072


Pre-made viral vector of VTN/Vitronectin cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001205Human VTN/V75/VN Lentivirus plasmidNM_0006387448HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001205Human VTN/V75/VN Lentivirus particleNM_0006387448HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm001542Mouse Vtn/AI256434/Vn Lentivirus plasmidNM_011707.222370MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm001542Mouse Vtn/AI256434/Vn Lentivirus particleNM_011707.222370MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


VTN/Vitronectin siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo7448Pre-made Human VTN/VN/V75 siRNA oligo Duplex7448HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo29169Pre-made Rat Vtn/Vn/Aa1018 siRNA oligo Duplex29169RatIn-vitro grade; in-vivo gradeDetail
pGMoligo22370Pre-made Mouse Vtn/Vn siRNA oligo Duplex22370MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo708499Pre-made Cynomolgus/Rhesus macaque VTN siRNA oligo Duplex708499Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101100765Pre-made Cat/Feline VTN siRNA oligo Duplex101100765Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo480621Pre-made Dog/Canine VTN siRNA oligo Duplex480621Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo507525Pre-made Bovines/Cattle VTN siRNA oligo Duplex507525Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100059034Pre-made Equine/Horse VTN siRNA oligo Duplex100059034Equine/HorseIn-vitro grade; in-vivo gradeDetail


VTN/Vitronectin antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-SE0548-AbHumanAnti-Human VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-rg-SE0548-AbRatAnti-Rat VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-mg-SE0548-AbMouseAnti-Mouse VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cynog-SE0548-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-felg-SE0548-AbCat/FelineAnti-Cat/Feline VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cang-SE0548-AbDog/CanineAnti-Dog/Canine VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-bovg-SE0548-AbBovines/CattleAnti-Bovines/Cattle VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-equg-SE0548-AbEquine/HorseAnti-Equine/Horse VTN/Vitronectin monoclonal antibodymabFACS/Biofunctional AntibodyDetail


VTN/Vitronectin recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-SE0548-AgHumanHuman VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-rg-SE0548-AgRatRat VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-mg-SE0548-AgMouseMouse VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-cynog-SE0548-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-felg-SE0548-AgCat/FelineCat/Feline VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-cang-SE0548-AgDog/CanineDog/Canine VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-bovg-SE0548-AgBovines/CattleBovines/Cattle VTN/Vitronectin recombinant proteinMammalian cellDetail
GM-Tg-equg-SE0548-AgEquine/HorseEquine/Horse VTN/Vitronectin recombinant proteinMammalian cellDetail