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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0520
|
| Target Name |
Tenascin-X/TNXB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7148
|
| Gene ID |
100059315 (Equus caballus), 100682877 (Canis lupus familiaris), 101101563 (Felis catus), 282654 (Bos taurus)
7148 (Homo sapiens), 716998 (Macaca mulatta), 81877 (Mus musculus)
|
| Target Alternative Names |
EDS3,EDSCLL,EDSCLL1,HXBL,Hexabrachion-like protein,TENX,TN-X,TNX,TNXB,TNXB1,TNXB2,TNXBS,Tenascin-X,Tn-mhc,Tnx,Tnxb,VUR8,XB,XBS
|
| Uniprot Accession |
P22105
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Human papillomavirus infection
|
| Gene Ensembl |
ENSECAG00000038712, ENSBTAG00000001444, ENSG00000168477, ENSMMUG00000000758, ENSMUSG00000033327
|
Tenascin-X/TNXB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7148 | Pre-made Human TNXB/XB/TNX siRNA oligo Duplex | 7148 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81877 | Pre-made Mouse Tnxb/Tnx/Tn-mhc siRNA oligo Duplex | 81877 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716998 | Pre-made Cynomolgus/Rhesus macaque TNXB siRNA oligo Duplex | 716998 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101563 | Pre-made Cat/Feline TNXB siRNA oligo Duplex | 101101563 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100682877 | Pre-made Dog/Canine TNXB siRNA oligo Duplex | 100682877 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282654 | Pre-made Bovines/Cattle TNXB/TNX siRNA oligo Duplex | 282654 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059315 | Pre-made Equine/Horse TNXB siRNA oligo Duplex | 100059315 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Tenascin-X/TNXB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0520-Ab | Human | Anti-Human Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0520-Ab | Mouse | Anti-Mouse Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0520-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0520-Ab | Cat/Feline | Anti-Cat/Feline Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0520-Ab | Dog/Canine | Anti-Dog/Canine Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0520-Ab | Bovines/Cattle | Anti-Bovines/Cattle Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0520-Ab | Equine/Horse | Anti-Equine/Horse Tenascin-X/TNXB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Tenascin-X/TNXB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0520-Ag | Human | Human Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0520-Ag | Mouse | Mouse Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0520-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0520-Ag | Cat/Feline | Cat/Feline Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0520-Ag | Dog/Canine | Dog/Canine Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0520-Ag | Bovines/Cattle | Bovines/Cattle Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0520-Ag | Equine/Horse | Equine/Horse Tenascin-X/TNXB recombinant protein | Mammalian cell | Detail |
