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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0322
|
| Target Name |
LRRN2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10446
|
| Gene ID |
100054439 (Equus caballus), 100429709 (Macaca mulatta), 101083057 (Felis catus), 10446 (Homo sapiens)
16980 (Mus musculus), 289020 (Rattus norvegicus), 488564 (Canis lupus familiaris), 767860 (Bos taurus)
|
| Target Alternative Names |
5730406J09Rik,FIGLER7,GAC1,Glioma amplified on chromosome 1 protein,LRANK1,LRRN2,LRRN5,Leucine-rich repeat neuronal protein 2,Leucine-rich repeat neuronal protein 5,Lrrn2,NLRR-2
|
| Uniprot Accession |
O75325
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000005887, ENSMMUG00000063658, ENSG00000170382, ENSMUSG00000026443
|
| Target Classification |
Tumor-associated antigen (TAA)
|
LRRN2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10446 | Pre-made Human LRRN2/GAC1/LRRN5 siRNA oligo Duplex | 10446 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289020 | Pre-made Rat Lrrn2 siRNA oligo Duplex | 289020 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16980 | Pre-made Mouse Lrrn2/NLRR-2/5730406J09Rik siRNA oligo Duplex | 16980 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100429709 | Pre-made Cynomolgus/Rhesus macaque LRRN2 siRNA oligo Duplex | 100429709 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083057 | Pre-made Cat/Feline LRRN2 siRNA oligo Duplex | 101083057 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488564 | Pre-made Dog/Canine LRRN2 siRNA oligo Duplex | 488564 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767860 | Pre-made Bovines/Cattle LRRN2/LRRN5 siRNA oligo Duplex | 767860 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054439 | Pre-made Equine/Horse LRRN2 siRNA oligo Duplex | 100054439 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LRRN2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0322-Ab | Human | Anti-Human LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0322-Ab | Rat | Anti-Rat LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0322-Ab | Mouse | Anti-Mouse LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0322-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0322-Ab | Cat/Feline | Anti-Cat/Feline LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0322-Ab | Dog/Canine | Anti-Dog/Canine LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0322-Ab | Bovines/Cattle | Anti-Bovines/Cattle LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0322-Ab | Equine/Horse | Anti-Equine/Horse LRRN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LRRN2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0322-Ag | Human | Human LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0322-Ag | Rat | Rat LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0322-Ag | Mouse | Mouse LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0322-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0322-Ag | Cat/Feline | Cat/Feline LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0322-Ag | Dog/Canine | Dog/Canine LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0322-Ag | Bovines/Cattle | Bovines/Cattle LRRN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0322-Ag | Equine/Horse | Equine/Horse LRRN2 recombinant protein | Mammalian cell | Detail |
