Explore IGFALS gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| Target ID |
GM-SE0279
|
| Target Name |
IGFALS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3483
|
| Gene ID |
111767589 (Equus caballus), 16005 (Mus musculus), 3483 (Homo sapiens), 490069 (Canis lupus familiaris)
532494 (Bos taurus), 722493 (Macaca mulatta), 79438 (Rattus norvegicus)
|
| Target Alternative Names |
ACLSD,ALS,Albs,Als,IGFALS,Igfals,Insulin-like growth factor-binding protein complex acid labile subunit
|
| Uniprot Accession |
P70389,P35858,P35859
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Growth hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000039211, ENSMUSG00000046070, ENSG00000099769, ENSCAFG00845019117, ENSBTAG00000033299
|
Pre-made viral vector of IGFALS cDNA Clones/ORF Plasmid
IGFALS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3483 | Pre-made Human IGFALS/ALS/ACLSD siRNA oligo Duplex | 3483 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79438 | Pre-made Rat Igfals/Als siRNA oligo Duplex | 79438 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16005 | Pre-made Mouse Igfals/ALS/Albs siRNA oligo Duplex | 16005 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722493 | Pre-made Cynomolgus/Rhesus macaque IGFALS siRNA oligo Duplex | 722493 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490069 | Pre-made Dog/Canine IGFALS siRNA oligo Duplex | 490069 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532494 | Pre-made Bovines/Cattle IGFALS siRNA oligo Duplex | 532494 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111767589 | Pre-made Equine/Horse IGFALS siRNA oligo Duplex | 111767589 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGFALS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0279-Ab | Human | Anti-Human IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0279-Ab | Rat | Anti-Rat IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0279-Ab | Mouse | Anti-Mouse IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0279-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0279-Ab | Dog/Canine | Anti-Dog/Canine IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0279-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0279-Ab | Equine/Horse | Anti-Equine/Horse IGFALS monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IGFALS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0279-Ag | Human | Human IGFALS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0279-Ag | Rat | Rat IGFALS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0279-Ag | Mouse | Mouse IGFALS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0279-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGFALS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0279-Ag | Dog/Canine | Dog/Canine IGFALS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0279-Ag | Bovines/Cattle | Bovines/Cattle IGFALS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0279-Ag | Equine/Horse | Equine/Horse IGFALS recombinant protein | Mammalian cell | Detail |
