Explore HTRA4 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]
| Target ID |
GM-SE0273
|
| Target Name |
HTRA4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
203100
|
| Gene ID |
100058701 (Equus caballus), 101098456 (Felis catus), 203100 (Homo sapiens), 306564 (Rattus norvegicus)
330723 (Mus musculus), 475580 (Canis lupus familiaris), 514946 (Bos taurus), 700875 (Macaca mulatta)
|
| Target Alternative Names |
HTRA4,Htra4,RGD1306242,B430206E18Rik
|
| Uniprot Accession |
P83105,D3ZKF5,A2RT60,E1BJW1
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000012377, ENSG00000169495, ENSMUSG00000037406, ENSCAFG00845011352, ENSBTAG00000019532, ENSMMUG00000006037
|
| Target Classification |
|
Pre-made viral vector of HTRA4 cDNA Clones/ORF Plasmid
HTRA4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo203100 | Pre-made Human HTRA4 siRNA oligo Duplex | 203100 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306564 | Pre-made Rat Htra4/RGD1306242 siRNA oligo Duplex | 306564 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo330723 | Pre-made Mouse Htra4/B430206E18Rik siRNA oligo Duplex | 330723 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700875 | Pre-made Cynomolgus/Rhesus macaque HTRA4 siRNA oligo Duplex | 700875 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098456 | Pre-made Cat/Feline HTRA4 siRNA oligo Duplex | 101098456 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475580 | Pre-made Dog/Canine HTRA4 siRNA oligo Duplex | 475580 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514946 | Pre-made Bovines/Cattle HTRA4 siRNA oligo Duplex | 514946 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058701 | Pre-made Equine/Horse HTRA4 siRNA oligo Duplex | 100058701 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTRA4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0273-Ab | Human | Anti-Human HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0273-Ab | Rat | Anti-Rat HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0273-Ab | Mouse | Anti-Mouse HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0273-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0273-Ab | Cat/Feline | Anti-Cat/Feline HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0273-Ab | Dog/Canine | Anti-Dog/Canine HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0273-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0273-Ab | Equine/Horse | Anti-Equine/Horse HTRA4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HTRA4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0273-Ag | Human | Human HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0273-Ag | Rat | Rat HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0273-Ag | Mouse | Mouse HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0273-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0273-Ag | Cat/Feline | Cat/Feline HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0273-Ag | Dog/Canine | Dog/Canine HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0273-Ag | Bovines/Cattle | Bovines/Cattle HTRA4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0273-Ag | Equine/Horse | Equine/Horse HTRA4 recombinant protein | Mammalian cell | Detail |
