Explore FREM1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011]
| Target ID |
GM-SE0224
|
| Target Name |
FREM1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
158326
|
| Gene ID |
100062297 (Equus caballus), 102899932 (Felis catus), 158326 (Homo sapiens), 298185 (Rattus norvegicus)
329872 (Mus musculus), 481547 (Canis lupus familiaris), 508018 (Bos taurus), 713874 (Macaca mulatta)
|
| Target Alternative Names |
BNAR,C9orf143,C9orf145,C9orf154,D430009N09,D630008K06,FRAS1-related extracellular matrix protein 1,FREM1,Frem1,MOTA,Protein QBRICK,RGD1306981,TILRR,TRIGNO2,crf11,eye,eyes2,heb,qbrick
|
| Uniprot Accession |
Q5H8C1,Q684R7
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
ECM-receptor interaction
|
| Gene Ensembl |
ENSECAG00000015567, ENSG00000164946, ENSMUSG00000059049, ENSCAFG00845011452, ENSBTAG00000020141, ENSMMUG00000008128
|
FREM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo158326 | Pre-made Human FREM1/BNAR/MOTA siRNA oligo Duplex | 158326 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298185 | Pre-made Rat Frem1/RGD1306981 siRNA oligo Duplex | 298185 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo329872 | Pre-made Mouse Frem1/heb/crf11 siRNA oligo Duplex | 329872 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713874 | Pre-made Cynomolgus/Rhesus macaque FREM1 siRNA oligo Duplex | 713874 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102899932 | Pre-made Cat/Feline FREM1 siRNA oligo Duplex | 102899932 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481547 | Pre-made Dog/Canine FREM1 siRNA oligo Duplex | 481547 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508018 | Pre-made Bovines/Cattle FREM1 siRNA oligo Duplex | 508018 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062297 | Pre-made Equine/Horse FREM1 siRNA oligo Duplex | 100062297 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FREM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0224-Ab | Human | Anti-Human FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0224-Ab | Rat | Anti-Rat FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0224-Ab | Mouse | Anti-Mouse FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0224-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0224-Ab | Cat/Feline | Anti-Cat/Feline FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0224-Ab | Dog/Canine | Anti-Dog/Canine FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0224-Ab | Bovines/Cattle | Anti-Bovines/Cattle FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0224-Ab | Equine/Horse | Anti-Equine/Horse FREM1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
FREM1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0224-Ag | Human | Human FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0224-Ag | Rat | Rat FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0224-Ag | Mouse | Mouse FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0224-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0224-Ag | Cat/Feline | Cat/Feline FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0224-Ag | Dog/Canine | Dog/Canine FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0224-Ag | Bovines/Cattle | Bovines/Cattle FREM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0224-Ag | Equine/Horse | Equine/Horse FREM1 recombinant protein | Mammalian cell | Detail |
