Explore FGF6 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0216
|
| Target Name |
FGF6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2251
|
| Gene ID |
100051221 (Equus caballus), 101091459 (Felis catus), 14177 (Mus musculus), 170700 (Rattus norvegicus)
2251 (Homo sapiens), 486735 (Canis lupus familiaris), 540317 (Bos taurus), 710739 (Macaca mulatta)
|
| Target Alternative Names |
FGF-6,FGF6,FGF7B,Fgf-6,Fgf6,Fgf7b,Fibroblast growth factor 6,HBGF-6,HST2,HSTF-2,HSTF-2),Heparin secretory-transforming protein 2 (HST-2,Heparin-binding growth factor 6 (HBGF-6)
|
| Uniprot Accession |
P21658,P10767
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Chemical carcinogenesis - receptor activation, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000022017, ENSMUSG00000000183, ENSG00000111241, ENSCAFG00845030655, ENSBTAG00000006800, ENSMMUG00000053967
|
Pre-made viral vector of FGF6 cDNA Clones/ORF Plasmid
FGF6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2251 | Pre-made Human FGF6/HST2/HBGF-6 siRNA oligo Duplex | 2251 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170700 | Pre-made Rat Fgf6/Fgf7b siRNA oligo Duplex | 170700 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14177 | Pre-made Mouse Fgf6/Fgf-6/Fgf7b siRNA oligo Duplex | 14177 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710739 | Pre-made Cynomolgus/Rhesus macaque FGF6 siRNA oligo Duplex | 710739 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091459 | Pre-made Cat/Feline FGF6 siRNA oligo Duplex | 101091459 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486735 | Pre-made Dog/Canine FGF6 siRNA oligo Duplex | 486735 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540317 | Pre-made Bovines/Cattle FGF6/FGF7B siRNA oligo Duplex | 540317 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051221 | Pre-made Equine/Horse FGF6/FGF7B siRNA oligo Duplex | 100051221 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0216-Ab | Human | Anti-Human FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0216-Ab | Rat | Anti-Rat FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0216-Ab | Mouse | Anti-Mouse FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0216-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0216-Ab | Cat/Feline | Anti-Cat/Feline FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0216-Ab | Dog/Canine | Anti-Dog/Canine FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0216-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0216-Ab | Equine/Horse | Anti-Equine/Horse FGF6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
FGF6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0216-Ag | Human | Human FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0216-Ag | Rat | Rat FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0216-Ag | Mouse | Mouse FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0216-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0216-Ag | Cat/Feline | Cat/Feline FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0216-Ag | Dog/Canine | Dog/Canine FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0216-Ag | Bovines/Cattle | Bovines/Cattle FGF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0216-Ag | Equine/Horse | Equine/Horse FGF6 recombinant protein | Mammalian cell | Detail |
