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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq, Jul 2009]
| Target ID |
GM-SE0100
|
| Target Name |
COL11A2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1302
|
| Gene ID |
100061226 (Equus caballus), 101085209 (Felis catus), 12815 (Mus musculus), 1302 (Homo sapiens) 294279 (Rattus norvegicus), 481734 (Canis lupus familiaris), 515435 (Bos taurus), 718050 (Macaca mulatta)
|
| Target Alternative Names |
COL11A2,Col11a2,Collagen alpha-2(XI) chain,DFNA13,DFNB53,FBCG2,HKE5,OSMEDA,OSMEDB,PARP,STL3
|
| Uniprot Accession |
Q64739,P13942,Q32S24
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Protein digestion and absorption
|
| Gene Ensembl |
ENSECAG00000029028, ENSMUSG00000024330, ENSG00000204248, ENSCAFG00845019587, ENSBTAG00000000601, ENSMMUG00000003850
|
COL11A2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1302 | Pre-made Human COL11A2/HKE5/PARP siRNA oligo Duplex | 1302 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294279 | Pre-made Rat Col11a2 siRNA oligo Duplex | 294279 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12815 | Pre-made Mouse Col11a2 siRNA oligo Duplex | 12815 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718050 | Pre-made Cynomolgus/Rhesus macaque COL11A2 siRNA oligo Duplex | 718050 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085209 | Pre-made Cat/Feline COL11A2 siRNA oligo Duplex | 101085209 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481734 | Pre-made Dog/Canine COL11A2 siRNA oligo Duplex | 481734 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515435 | Pre-made Bovines/Cattle COL11A2 siRNA oligo Duplex | 515435 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061226 | Pre-made Equine/Horse COL11A2 siRNA oligo Duplex | 100061226 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
COL11A2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0100-Ab | Human | Anti-Human COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0100-Ab | Rat | Anti-Rat COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0100-Ab | Mouse | Anti-Mouse COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0100-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0100-Ab | Cat/Feline | Anti-Cat/Feline COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0100-Ab | Dog/Canine | Anti-Dog/Canine COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0100-Ab | Bovines/Cattle | Anti-Bovines/Cattle COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0100-Ab | Equine/Horse | Anti-Equine/Horse COL11A2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
COL11A2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0100-Ag | Human | Human COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0100-Ag | Rat | Rat COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0100-Ag | Mouse | Mouse COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0100-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0100-Ag | Cat/Feline | Cat/Feline COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0100-Ag | Dog/Canine | Dog/Canine COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0100-Ag | Bovines/Cattle | Bovines/Cattle COL11A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0100-Ag | Equine/Horse | Equine/Horse COL11A2 recombinant protein | Mammalian cell | Detail |