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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010]
| Target ID |
GM-SE0074
|
| Target Name |
CD1e/CD1E
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
913
|
| Gene ID |
913 (Homo sapiens)
|
| Target Alternative Names |
CD1A,CD1E,CD1e,R2,R2G1,T-cell surface glycoprotein CD1e,hCD1e,membrane-associated
|
| Uniprot Accession |
P15812
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Tight junction, Hematopoietic cell lineage, Amoebiasis
|
| Gene Ensembl |
ENSG00000158488
|
CD1e/CD1E siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo913 | Pre-made Human CD1E/R2/CD1A siRNA oligo Duplex | 913 | Human | In-vitro grade; in-vivo grade | Detail |
CD1e/CD1E antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0074-Ab | Human | Anti-Human CD1e/CD1E monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD1e/CD1E recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0074-Ag | Human | Human CD1e/CD1E recombinant protein | Mammalian cell | Detail |
