Explore CCL7 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0072
|
| Target Name |
CCL7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6354
|
| Gene ID |
6354 (Homo sapiens), 714751 (Macaca mulatta)
|
| Target Alternative Names |
C-C motif chemokine 7,CCL7,FIC,MARC,MCP-3,MCP3,Monocyte chemoattractant protein 3,Monocyte chemotactic protein 3 (MCP-3),NC28,SCYA6,SCYA7,Small-inducible cytokine A7
|
| Uniprot Accession |
P80098
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, IL-17 signaling pathway
|
| Gene Ensembl |
ENSG00000108688, ENSMMUG00000009782
|
Pre-made viral vector of CCL7 cDNA Clones/ORF Plasmid
CCL7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6354 | Pre-made Human CCL7/FIC/MARC siRNA oligo Duplex | 6354 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714751 | Pre-made Cynomolgus/Rhesus macaque CCL7 siRNA oligo Duplex | 714751 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CCL7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0072-Ab | Human | Anti-Human CCL7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0072-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCL7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
CCL7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0072-Ag | Human | Human CCL7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0072-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCL7 recombinant protein | Mammalian cell | Detail |
