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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
| Target ID |
GM-MP2605
|
| Target Name |
MUC2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4583
|
| Gene ID |
101096605 (Felis catus), 119864303 (Canis lupus familiaris), 17831 (Mus musculus), 24572 (Rattus norvegicus) 4583 (Homo sapiens), 720903 (Macaca mulatta), 789571 (Bos taurus)
|
| Target Alternative Names |
2010015E03Rik,AABR07006030.1,HH-Muc,Intestinal mucin-2,MCM,MLP,MUC-2,MUC2,Muc2,Mucin-2,SMUC,mucin-2,wnn
|
| Uniprot Accession |
Q80Z19,P98089,Q62635,Q02817
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Amoebiasis, Gastric cancer
|
| Gene Ensembl |
ENSMUSG00000025515, ENSG00000198788
|
| Target Classification |
Tumor-associated antigen (TAA)
|
MUC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4583 | Pre-made Human MUC2/MLP/SMUC siRNA oligo Duplex | 4583 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24572 | Pre-made Rat Muc2/MLP/HH-Muc siRNA oligo Duplex | 24572 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17831 | Pre-made Mouse Muc2/MCM/wnn siRNA oligo Duplex | 17831 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720903 | Pre-made Cynomolgus/Rhesus macaque MUC2 siRNA oligo Duplex | 720903 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096605 | Pre-made Cat/Feline MUC2 siRNA oligo Duplex | 101096605 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119864303 | Pre-made Dog/Canine MUC2 siRNA oligo Duplex | 119864303 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789571 | Pre-made Bovines/Cattle MUC2/mucin-2 siRNA oligo Duplex | 789571 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
MUC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2605-Ab | Human | Anti-Human MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2605-Ab | Rat | Anti-Rat MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2605-Ab | Mouse | Anti-Mouse MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2605-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2605-Ab | Cat/Feline | Anti-Cat/Feline MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2605-Ab | Dog/Canine | Anti-Dog/Canine MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2605-Ab | Bovines/Cattle | Anti-Bovines/Cattle MUC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
MUC2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2605-Ag | Human | Human MUC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2605-Ag | Rat | Rat MUC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2605-Ag | Mouse | Mouse MUC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2605-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MUC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2605-Ag | Cat/Feline | Cat/Feline MUC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2605-Ag | Dog/Canine | Dog/Canine MUC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2605-Ag | Bovines/Cattle | Bovines/Cattle MUC2 VLP (virus-like particle) | HEK293 | Products Developing |