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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2596
|
| Target Name |
CYP2C19
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1557
|
| Gene ID |
1557 (Homo sapiens)
|
| Target Alternative Names |
(R)-limonene 6-monooxygenase,(S)-limonene 6-monooxygenase,(S)-limonene 7-monooxygenase,CPCJ,CYP2C,CYP2C19,CYPIIC17,CYPIIC19,Cytochrome P450 2C19,Cytochrome P450-11A,Cytochrome P450-254C,Fenbendazole monooxygenase (4'-hydroxylating),Mephenytoin 4-hydroxylase,P450C2C,P450IIC19
|
| Uniprot Accession |
P33261
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Serotonergic synapse, Chemical carcinogenesis - DNA adducts, Arachidonic acid metabolism, Linoleic acid metabolism, Drug metabolism - cytochrome P450
|
| Gene Ensembl |
ENSG00000165841
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CYP2C19 cDNA Clones/ORF Plasmid
CYP2C19 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1557 | Pre-made Human CYP2C19/CPCJ/CYP2C siRNA oligo Duplex | 1557 | Human | In-vitro grade; in-vivo grade | Detail |
CYP2C19 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2596-Ab | Human | Anti-Human CYP2C19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CYP2C19 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2596-Ag | Human | Human CYP2C19 VLP (virus-like particle) | HEK293 | Products Developing |
