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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2582
|
| Target Name |
CYP2C18
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1562
|
| Gene ID |
1562 (Homo sapiens), 701855 (Macaca mulatta)
|
| Target Alternative Names |
CYP2C18,CPCI,CYP2C,CYP2C17,P450IIC17,P450-6B/29C
|
| Uniprot Accession |
P33260
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Serotonergic synapse, Chemical carcinogenesis - DNA adducts, Retinol metabolism
|
| Gene Ensembl |
ENSG00000108242, ENSMMUG00000018330
|
| Target Classification |
|
Pre-made viral vector of CYP2C18 cDNA Clones/ORF Plasmid
CYP2C18 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1562 | Pre-made Human CYP2C18/CPCI/CYP2C siRNA oligo Duplex | 1562 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701855 | Pre-made Cynomolgus/Rhesus macaque CYP2C18 siRNA oligo Duplex | 701855 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CYP2C18 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2582-Ab | Human | Anti-Human CYP2C18 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2582-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYP2C18 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CYP2C18 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2582-Ag | Human | Human CYP2C18 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2582-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYP2C18 VLP (virus-like particle) | HEK293 | Products Developing |
