Explore MUC5B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]
| Target ID |
GM-MP2551
|
| Target Name |
MUC5B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
727897
|
| Gene ID |
100429390 (Macaca mulatta), 101096354 (Felis catus), 102147792 (Equus caballus), 309114 (Rattus norvegicus)
483656 (Canis lupus familiaris), 727897 (Homo sapiens), 74180 (Mus musculus), 789503 (Bos taurus)
|
| Target Alternative Names |
2300002I04Rik,A130042M24,Cervical mucin,High molecular weight salivary mucin MG1,MG1,MUC-5B,MUC5,MUC5AC,MUC5B,MUC9,Muc5b,Mucin-5 subtype B,Mucin-5B,RGD1561983,Sublingual gland mucin,mucin 5b,tracheobronchial
|
| Uniprot Accession |
Q9HC84
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
IL-17 signaling pathway, Salivary secretion
|
| Gene Ensembl |
ENSG00000117983, ENSMUSG00000066108
|
| Target Classification |
Tumor-associated antigen (TAA)
|
MUC5B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo727897 | Pre-made Human MUC5B/MG1/MUC5 siRNA oligo Duplex | 727897 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo309114 | Pre-made Rat Muc5b/RGD1561983 siRNA oligo Duplex | 309114 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74180 | Pre-made Mouse Muc5b/MUC5/MUC9 siRNA oligo Duplex | 74180 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100429390 | Pre-made Cynomolgus/Rhesus macaque MUC5B siRNA oligo Duplex | 100429390 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096354 | Pre-made Cat/Feline MUC5B siRNA oligo Duplex | 101096354 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483656 | Pre-made Dog/Canine MUC5B siRNA oligo Duplex | 483656 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789503 | Pre-made Bovines/Cattle MUC5B/MUC5AC siRNA oligo Duplex | 789503 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102147792 | Pre-made Equine/Horse MUC5B siRNA oligo Duplex | 102147792 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MUC5B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2551-Ab | Human | Anti-Human MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2551-Ab | Rat | Anti-Rat MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2551-Ab | Mouse | Anti-Mouse MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2551-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2551-Ab | Cat/Feline | Anti-Cat/Feline MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2551-Ab | Dog/Canine | Anti-Dog/Canine MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2551-Ab | Bovines/Cattle | Anti-Bovines/Cattle MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2551-Ab | Equine/Horse | Anti-Equine/Horse MUC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
MUC5B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2551-Ag | Human | Human MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2551-Ag | Rat | Rat MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2551-Ag | Mouse | Mouse MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2551-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2551-Ag | Cat/Feline | Cat/Feline MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2551-Ag | Dog/Canine | Dog/Canine MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2551-Ag | Bovines/Cattle | Bovines/Cattle MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2551-Ag | Equine/Horse | Equine/Horse MUC5B VLP (virus-like particle) | HEK293 | Products Developing |
