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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Nov 2014]
| Target ID |
GM-MP2435
|
| Target Name |
HRG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3273
|
| Gene ID |
100068112 (Equus caballus), 100683193 (Canis lupus familiaris), 101082002 (Felis catus), 171016 (Rattus norvegicus)
280820 (Bos taurus), 3273 (Homo sapiens), 699100 (Macaca mulatta), 94175 (Mus musculus)
|
| Target Alternative Names |
HRG,Hrg,HPRG,HRG1,HRGP,THPH11,Hprg,Hrgp,D16jh2,D18020
|
| Uniprot Accession |
Q99PS8,P33433,P04196,Q9ESB3
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000013388, ENSCAFG00845021042, ENSBTAG00000001265, ENSG00000113905, ENSMMUG00000018910, ENSMUSG00000022877
|
| Target Classification |
|
HRG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3273 | Pre-made Human HRG/HPRG/HRGP siRNA oligo Duplex | 3273 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171016 | Pre-made Rat Hrg/HPRG/HRG1 siRNA oligo Duplex | 171016 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo94175 | Pre-made Mouse Hrg/Hprg/Hrgp siRNA oligo Duplex | 94175 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699100 | Pre-made Cynomolgus/Rhesus macaque HRG siRNA oligo Duplex | 699100 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082002 | Pre-made Cat/Feline HRG siRNA oligo Duplex | 101082002 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100683193 | Pre-made Dog/Canine HRG siRNA oligo Duplex | 100683193 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280820 | Pre-made Bovines/Cattle HRG/HPRG siRNA oligo Duplex | 280820 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068112 | Pre-made Equine/Horse HRG siRNA oligo Duplex | 100068112 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HRG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2435-Ab | Human | Anti-Human HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2435-Ab | Rat | Anti-Rat HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2435-Ab | Mouse | Anti-Mouse HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2435-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2435-Ab | Cat/Feline | Anti-Cat/Feline HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2435-Ab | Dog/Canine | Anti-Dog/Canine HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2435-Ab | Bovines/Cattle | Anti-Bovines/Cattle HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2435-Ab | Equine/Horse | Anti-Equine/Horse HRG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HRG VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2435-Ag | Human | Human HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2435-Ag | Rat | Rat HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2435-Ag | Mouse | Mouse HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2435-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2435-Ag | Cat/Feline | Cat/Feline HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2435-Ag | Dog/Canine | Dog/Canine HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2435-Ag | Bovines/Cattle | Bovines/Cattle HRG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2435-Ag | Equine/Horse | Equine/Horse HRG VLP (virus-like particle) | HEK293 | Products Developing |
