Explore C8G gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011]
| Target ID |
GM-MP2424
|
| Target Name |
C8G
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
733
|
| Gene ID |
100147492 (Equus caballus), 101098834 (Felis catus), 296545 (Rattus norvegicus), 480672 (Canis lupus familiaris)
517356 (Bos taurus), 69379 (Mus musculus), 721647 (Macaca mulatta), 733 (Homo sapiens)
|
| Target Alternative Names |
C8G,C8g,C8C
|
| Uniprot Accession |
Q8VCG4,P07360
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Complement and coagulation cascades, Amoebiasis
|
| Gene Ensembl |
ENSECAG00000013192, ENSCAFG00845005165, ENSMUSG00000015083, ENSMMUG00000032142, ENSG00000176919
|
| Target Classification |
|
C8G siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo733 | Pre-made Human C8G/C8C siRNA oligo Duplex | 733 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296545 | Pre-made Rat C8g siRNA oligo Duplex | 296545 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo69379 | Pre-made Mouse C8g siRNA oligo Duplex | 69379 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721647 | Pre-made Cynomolgus/Rhesus macaque C8G siRNA oligo Duplex | 721647 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098834 | Pre-made Cat/Feline C8G siRNA oligo Duplex | 101098834 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480672 | Pre-made Dog/Canine C8G siRNA oligo Duplex | 480672 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517356 | Pre-made Bovines/Cattle C8G siRNA oligo Duplex | 517356 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147492 | Pre-made Equine/Horse C8G siRNA oligo Duplex | 100147492 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
C8G antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2424-Ab | Human | Anti-Human C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2424-Ab | Rat | Anti-Rat C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2424-Ab | Mouse | Anti-Mouse C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2424-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2424-Ab | Cat/Feline | Anti-Cat/Feline C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2424-Ab | Dog/Canine | Anti-Dog/Canine C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2424-Ab | Bovines/Cattle | Anti-Bovines/Cattle C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2424-Ab | Equine/Horse | Anti-Equine/Horse C8G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
C8G VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2424-Ag | Human | Human C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2424-Ag | Rat | Rat C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2424-Ag | Mouse | Mouse C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2424-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2424-Ag | Cat/Feline | Cat/Feline C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2424-Ag | Dog/Canine | Dog/Canine C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2424-Ag | Bovines/Cattle | Bovines/Cattle C8G VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2424-Ag | Equine/Horse | Equine/Horse C8G VLP (virus-like particle) | HEK293 | Products Developing |
