Explore Talin-1/TLN1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
| Target ID |
GM-MP2356
|
| Target Name |
Talin-1/TLN1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7094
|
| Gene ID |
100055501 (Equus caballus), 100856393 (Canis lupus familiaris), 101093057 (Felis catus), 21894 (Mus musculus) 313494 (Rattus norvegicus), 696298 (Macaca mulatta), 7094 (Homo sapiens), 783470 (Bos taurus)
|
| Target Alternative Names |
ILWEQ,TLN,TLN1,Talin-1,Tln,Tln1,talin-1
|
| Uniprot Accession |
P26039,Q9Y490
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Mucocutaneous lymph node syndrome [Kawasaki]
|
| Disease from KEGG |
Rap1 signaling pathway, Focal adhesion, Platelet activation, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000016464, ENSCAFG00845009262, ENSMUSG00000028465, ENSMMUG00000031856, ENSG00000137076, ENSBTAG00000025868
|
Talin-1/TLN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7094 | Pre-made Human TLN1/TLN/ILWEQ siRNA oligo Duplex | 7094 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313494 | Pre-made Rat Tln1/Tln siRNA oligo Duplex | 313494 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21894 | Pre-made Mouse Tln1/Tln siRNA oligo Duplex | 21894 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696298 | Pre-made Cynomolgus/Rhesus macaque TLN1/talin-1 siRNA oligo Duplex | 696298 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093057 | Pre-made Cat/Feline TLN1 siRNA oligo Duplex | 101093057 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856393 | Pre-made Dog/Canine TLN1 siRNA oligo Duplex | 100856393 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783470 | Pre-made Bovines/Cattle TLN1 siRNA oligo Duplex | 783470 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055501 | Pre-made Equine/Horse TLN1 siRNA oligo Duplex | 100055501 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Talin-1/TLN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2356-Ab | Human | Anti-Human Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2356-Ab | Rat | Anti-Rat Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2356-Ab | Mouse | Anti-Mouse Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2356-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2356-Ab | Cat/Feline | Anti-Cat/Feline Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2356-Ab | Dog/Canine | Anti-Dog/Canine Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2356-Ab | Bovines/Cattle | Anti-Bovines/Cattle Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2356-Ab | Equine/Horse | Anti-Equine/Horse Talin-1/TLN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Talin-1/TLN1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2356-Ag | Human | Human Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2356-Ag | Rat | Rat Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2356-Ag | Mouse | Mouse Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2356-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2356-Ag | Cat/Feline | Cat/Feline Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2356-Ag | Dog/Canine | Dog/Canine Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2356-Ag | Bovines/Cattle | Bovines/Cattle Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2356-Ag | Equine/Horse | Equine/Horse Talin-1/TLN1 VLP (virus-like particle) | HEK293 | Products Developing |