Explore SLC9A3R2/NHERF2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
| Target ID |
GM-MP2330
|
| Target Name |
SLC9A3R2/NHERF2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9351
|
| Gene ID |
100146142 (Equus caballus), 101082539 (Felis catus), 116501 (Rattus norvegicus), 479884 (Canis lupus familiaris)
65962 (Mus musculus), 694658 (Macaca mulatta), 768005 (Bos taurus), 9351 (Homo sapiens)
|
| Target Alternative Names |
0610011L07Rik,1200011K07Rik,2010007A20Rik,E3KARP,E3karp,NHE3 kinase A regulatory protein E3KARP,NHE3RF2,NHERF-2,NHERF2,Na(+)/H(+) exchange regulatory cofactor NHE-RF2,Nherf2,OCTS2,Octs2,SIP-1,SIP1,SLC9A3R2,SRY-interacting protein 1 (SIP-1),Sip-1,Sip1,Slc9a3r2,Sodium-hydrogen exchanger regulatory factor 2,Solute carrier family 9 isoform A3 regulatory factor 2,Sryip1,TKA-1,Tka-1,Tyrosine kinase activator protein 1 (TKA-1)
|
| Uniprot Accession |
Q920G2,Q9JHL1,Q15599
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Aldosterone-regulated sodium reabsorption
|
| Gene Ensembl |
ENSECAG00000013367, ENSCAFG00845017011, ENSMUSG00000002504, ENSMMUG00000002806, ENSBTAG00000013479, ENSG00000065054
|
| Target Classification |
|
SLC9A3R2/NHERF2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9351 | Pre-made Human NHERF2/SIP1/OCTS2 siRNA oligo Duplex | 9351 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116501 | Pre-made Rat Nherf2/E3karp/Slc9a3r2 siRNA oligo Duplex | 116501 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65962 | Pre-made Mouse Nherf2/Sip1/Octs2 siRNA oligo Duplex | 65962 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694658 | Pre-made Cynomolgus/Rhesus macaque NHERF2/SLC9A3R2 siRNA oligo Duplex | 694658 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082539 | Pre-made Cat/Feline NHERF2/SLC9A3R2 siRNA oligo Duplex | 101082539 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479884 | Pre-made Dog/Canine NHERF2/SLC9A3R2 siRNA oligo Duplex | 479884 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo768005 | Pre-made Bovines/Cattle NHERF2/SLC9A3R2 siRNA oligo Duplex | 768005 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146142 | Pre-made Equine/Horse NHERF2/SLC9A3R2 siRNA oligo Duplex | 100146142 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SLC9A3R2/NHERF2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2330-Ab | Human | Anti-Human SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2330-Ab | Rat | Anti-Rat SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2330-Ab | Mouse | Anti-Mouse SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2330-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2330-Ab | Cat/Feline | Anti-Cat/Feline SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2330-Ab | Dog/Canine | Anti-Dog/Canine SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2330-Ab | Bovines/Cattle | Anti-Bovines/Cattle SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2330-Ab | Equine/Horse | Anti-Equine/Horse SLC9A3R2/NHERF2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SLC9A3R2/NHERF2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2330-Ag | Human | Human SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2330-Ag | Rat | Rat SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2330-Ag | Mouse | Mouse SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2330-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2330-Ag | Cat/Feline | Cat/Feline SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2330-Ag | Dog/Canine | Dog/Canine SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2330-Ag | Bovines/Cattle | Bovines/Cattle SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2330-Ag | Equine/Horse | Equine/Horse SLC9A3R2/NHERF2 VLP (virus-like particle) | HEK293 | Products Developing |
