Explore SIPA1L3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene belongs to the signal induced proliferation associated 1 family of genes, which encode GTPase-activating proteins specific for the GTP-binding protein Rap1. Rap1 has been implicated in regulation of cell adhesion, cell polarity, and organization of the cytoskeleton. Like other members of the family, the protein encoded by this gene contains RapGAP and PDZ domains. In addition, this protein contains a C-terminal leucine zipper domain. This gene is proposed to function in epithelial cell morphogenesis and establishment or maintenance of polarity. Consistently, expression of the protein in cell culture showed localization to cell-cell borders in apical regions, and downregulation of the gene in 3D Caco2 cell culture resulted in abnormal cell polarity and morphogenesis. Allelic variants of this gene have been associated with congenital cataracts in humans. [provided by RefSeq, Feb 2016]
| Target ID |
GM-MP2327
|
| Target Name |
SIPA1L3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23094
|
| Gene ID |
100063981 (Equus caballus), 101096689 (Felis catus), 23094 (Homo sapiens), 292771 (Rattus norvegicus)
513625 (Bos taurus), 612583 (Canis lupus familiaris), 714601 (Macaca mulatta), 74206 (Mus musculus)
|
| Target Alternative Names |
SIPA1L3,Sipa1l3,SPAL3,SPAR3,CTRCT45,2610511M17Rik
|
| Uniprot Accession |
O60292,G3X9J0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Rap1 signaling pathway
|
| Gene Ensembl |
ENSECAG00000023553, ENSG00000105738, ENSBTAG00000018225, ENSCAFG00845006405, ENSMMUG00000003492, ENSMUSG00000030583
|
| Target Classification |
|
SIPA1L3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23094 | Pre-made Human SIPA1L3/SPAL3/SPAR3 siRNA oligo Duplex | 23094 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292771 | Pre-made Rat Sipa1l3 siRNA oligo Duplex | 292771 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74206 | Pre-made Mouse Sipa1l3/2610511M17Rik siRNA oligo Duplex | 74206 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714601 | Pre-made Cynomolgus/Rhesus macaque SIPA1L3 siRNA oligo Duplex | 714601 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096689 | Pre-made Cat/Feline SIPA1L3 siRNA oligo Duplex | 101096689 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612583 | Pre-made Dog/Canine SIPA1L3 siRNA oligo Duplex | 612583 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513625 | Pre-made Bovines/Cattle SIPA1L3 siRNA oligo Duplex | 513625 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063981 | Pre-made Equine/Horse SIPA1L3 siRNA oligo Duplex | 100063981 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SIPA1L3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2327-Ab | Human | Anti-Human SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2327-Ab | Rat | Anti-Rat SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2327-Ab | Mouse | Anti-Mouse SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2327-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2327-Ab | Cat/Feline | Anti-Cat/Feline SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2327-Ab | Dog/Canine | Anti-Dog/Canine SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2327-Ab | Bovines/Cattle | Anti-Bovines/Cattle SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2327-Ab | Equine/Horse | Anti-Equine/Horse SIPA1L3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SIPA1L3 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2327-Ag | Human | Human SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2327-Ag | Rat | Rat SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2327-Ag | Mouse | Mouse SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2327-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2327-Ag | Cat/Feline | Cat/Feline SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2327-Ag | Dog/Canine | Dog/Canine SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2327-Ag | Bovines/Cattle | Bovines/Cattle SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2327-Ag | Equine/Horse | Equine/Horse SIPA1L3 VLP (virus-like particle) | HEK293 | Products Developing |
