Explore SHROOM2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
| Target ID |
GM-MP2325
|
| Target Name |
SHROOM2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
357
|
| Gene ID |
100052577 (Equus caballus), 101087301 (Felis catus), 110380 (Mus musculus), 317435 (Rattus norvegicus)
357 (Homo sapiens), 491734 (Canis lupus familiaris), 523644 (Bos taurus), 720802 (Macaca mulatta)
|
| Target Alternative Names |
4832440C16,APXL,Ab2-404,Apical-like protein,Apxl,C630003H05Rik,HSAPXL,Protein APXL,Protein Shroom2,SHROOM2,Shrm2,Shroom2
|
| Uniprot Accession |
A2ALU4,Q7TP36,Q13796
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000012150, ENSMUSG00000045180, ENSG00000146950, ENSBTAG00000000211, ENSMMUG00000006193
|
| Target Classification |
|
SHROOM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo357 | Pre-made Human SHROOM2/APXL/HSAPXL siRNA oligo Duplex | 357 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317435 | Pre-made Rat Shroom2/Apxl/Ab2-404 siRNA oligo Duplex | 317435 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110380 | Pre-made Mouse Shroom2/Apxl/Shrm2 siRNA oligo Duplex | 110380 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720802 | Pre-made Cynomolgus/Rhesus macaque SHROOM2/APXL siRNA oligo Duplex | 720802 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087301 | Pre-made Cat/Feline SHROOM2 siRNA oligo Duplex | 101087301 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491734 | Pre-made Dog/Canine SHROOM2 siRNA oligo Duplex | 491734 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523644 | Pre-made Bovines/Cattle SHROOM2 siRNA oligo Duplex | 523644 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052577 | Pre-made Equine/Horse SHROOM2 siRNA oligo Duplex | 100052577 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SHROOM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2325-Ab | Human | Anti-Human SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2325-Ab | Rat | Anti-Rat SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2325-Ab | Mouse | Anti-Mouse SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2325-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2325-Ab | Cat/Feline | Anti-Cat/Feline SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2325-Ab | Dog/Canine | Anti-Dog/Canine SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2325-Ab | Bovines/Cattle | Anti-Bovines/Cattle SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2325-Ab | Equine/Horse | Anti-Equine/Horse SHROOM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SHROOM2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2325-Ag | Human | Human SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2325-Ag | Rat | Rat SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2325-Ag | Mouse | Mouse SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2325-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2325-Ag | Cat/Feline | Cat/Feline SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2325-Ag | Dog/Canine | Dog/Canine SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2325-Ag | Bovines/Cattle | Bovines/Cattle SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2325-Ag | Equine/Horse | Equine/Horse SHROOM2 VLP (virus-like particle) | HEK293 | Products Developing |
