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Target
sublocation: Transmembrane Protein.
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
| Target ID |
GM-MP2267
|
| Target Name |
PRC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9055
|
| Gene ID |
100069001 (Equus caballus), 101088580 (Felis catus), 233406 (Mus musculus), 308761 (Rattus norvegicus)
488742 (Canis lupus familiaris), 710182 (Macaca mulatta), 767818 (Bos taurus), 9055 (Homo sapiens)
|
| Target Alternative Names |
ASE1,D7Ertd348e,MAP65,PRC1,Prc1,Protein regulator of cytokinesis 1
|
| Uniprot Accession |
Q99K43,O43663
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000017906, ENSMUSG00000038943, ENSCAFG00845001624, ENSMMUG00000007534, ENSBTAG00000018643, ENSG00000198901
|
| Target Classification |
|
Pre-made viral vector of PRC1 cDNA Clones/ORF Plasmid
PRC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9055 | Pre-made Human PRC1/ASE1/MAP65 siRNA oligo Duplex | 9055 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308761 | Pre-made Rat Prc1 siRNA oligo Duplex | 308761 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo233406 | Pre-made Mouse Prc1/D7Ertd348e siRNA oligo Duplex | 233406 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710182 | Pre-made Cynomolgus/Rhesus macaque PRC1 siRNA oligo Duplex | 710182 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088580 | Pre-made Cat/Feline PRC1 siRNA oligo Duplex | 101088580 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488742 | Pre-made Dog/Canine PRC1 siRNA oligo Duplex | 488742 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767818 | Pre-made Bovines/Cattle PRC1 siRNA oligo Duplex | 767818 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069001 | Pre-made Equine/Horse PRC1 siRNA oligo Duplex | 100069001 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2267-Ab | Human | Anti-Human PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2267-Ab | Rat | Anti-Rat PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2267-Ab | Mouse | Anti-Mouse PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2267-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2267-Ab | Cat/Feline | Anti-Cat/Feline PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2267-Ab | Dog/Canine | Anti-Dog/Canine PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2267-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2267-Ab | Equine/Horse | Anti-Equine/Horse PRC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PRC1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2267-Ag | Human | Human PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2267-Ag | Rat | Rat PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2267-Ag | Mouse | Mouse PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2267-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2267-Ag | Cat/Feline | Cat/Feline PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2267-Ag | Dog/Canine | Dog/Canine PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2267-Ag | Bovines/Cattle | Bovines/Cattle PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2267-Ag | Equine/Horse | Equine/Horse PRC1 VLP (virus-like particle) | HEK293 | Products Developing |
