Explore PIP4K2A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2243
|
| Target Name |
PIP4K2A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5305
|
| Gene ID |
100066733 (Equus caballus), 101096576 (Felis catus), 116723 (Rattus norvegicus), 18718 (Mus musculus)
5305 (Homo sapiens), 533289 (Bos taurus), 608414 (Canis lupus familiaris), 710724 (Macaca mulatta)
|
| Target Alternative Names |
1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PI5P4KA,PIP4K2A,PIP4KII-alpha),PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIP5KIII,PIPK,Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4Kalpha),Phosphatidylinositol 5-phosphate 4-kinase type II alpha (PI(5)P 4-kinase type II alpha,Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha,Pip4k2a,Pip5k2a,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha
|
| Uniprot Accession |
Q9R0I8,O70172,P48426
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways, Regulation of actin cytoskeleton
|
| Gene Ensembl |
ENSECAG00000007707, ENSMUSG00000026737, ENSG00000150867, ENSBTAG00000018033, ENSCAFG00845007359, ENSMMUG00000015034
|
| Target Classification |
Kinase
|
Pre-made viral vector of PIP4K2A cDNA Clones/ORF Plasmid
PIP4K2A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5305 | Pre-made Human PIP4K2A/PIPK/PI5P4KA siRNA oligo Duplex | 5305 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116723 | Pre-made Rat Pip4k2a/Pip5k2a siRNA oligo Duplex | 116723 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18718 | Pre-made Mouse Pip4k2a/Pip5k2a siRNA oligo Duplex | 18718 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710724 | Pre-made Cynomolgus/Rhesus macaque PIP4K2A/PIP5K2A siRNA oligo Duplex | 710724 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096576 | Pre-made Cat/Feline PIP4K2A siRNA oligo Duplex | 101096576 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608414 | Pre-made Dog/Canine PIP4K2A/PIP5K2A siRNA oligo Duplex | 608414 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533289 | Pre-made Bovines/Cattle PIP4K2A siRNA oligo Duplex | 533289 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066733 | Pre-made Equine/Horse PIP4K2A siRNA oligo Duplex | 100066733 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PIP4K2A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2243-Ab | Human | Anti-Human PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2243-Ab | Rat | Anti-Rat PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2243-Ab | Mouse | Anti-Mouse PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2243-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2243-Ab | Cat/Feline | Anti-Cat/Feline PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2243-Ab | Dog/Canine | Anti-Dog/Canine PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2243-Ab | Bovines/Cattle | Anti-Bovines/Cattle PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2243-Ab | Equine/Horse | Anti-Equine/Horse PIP4K2A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PIP4K2A VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2243-Ag | Human | Human PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2243-Ag | Rat | Rat PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2243-Ag | Mouse | Mouse PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2243-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2243-Ag | Cat/Feline | Cat/Feline PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2243-Ag | Dog/Canine | Dog/Canine PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2243-Ag | Bovines/Cattle | Bovines/Cattle PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2243-Ag | Equine/Horse | Equine/Horse PIP4K2A VLP (virus-like particle) | HEK293 | Products Developing |
