Explore PIK3R6 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
| Target ID |
GM-MP2242
|
| Target Name |
PIK3R6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
146850
|
| Gene ID |
100062779 (Equus caballus), 101082104 (Felis catus), 104709 (Mus musculus), 146850 (Homo sapiens)
497932 (Rattus norvegicus), 515621 (Bos taurus), 608225 (Canis lupus familiaris), 722023 (Macaca mulatta)
|
| Target Alternative Names |
PIK3R6,Pik3r6,p84,p87PIKAP,p84 PIKAP,p87(PIKAP),C17orf38,HsT41028,RGD1560850
|
| Uniprot Accession |
Q3U6Q4,Q5UE93
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
cGMP-PKG signaling pathway, Chemokine signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes, Platelet activation, Cholinergic synapse, Oxytocin signaling pathway, Toxoplasmosis, Kaposi sarcoma-associated herpesvirus infection
|
| Gene Ensembl |
ENSECAG00000017146, ENSMUSG00000046207, ENSG00000276231, ENSBTAG00000016344, ENSCAFG00845000997, ENSMMUG00000005791
|
| Target Classification |
|
Pre-made viral vector of PIK3R6 cDNA Clones/ORF Plasmid
PIK3R6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo146850 | Pre-made Human PIK3R6/C17orf38/HsT41028 siRNA oligo Duplex | 146850 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497932 | Pre-made Rat Pik3r6/RGD1560850 siRNA oligo Duplex | 497932 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo104709 | Pre-made Mouse Pik3r6/p84/p87PIKAP siRNA oligo Duplex | 104709 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722023 | Pre-made Cynomolgus/Rhesus macaque PIK3R6 siRNA oligo Duplex | 722023 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082104 | Pre-made Cat/Feline PIK3R6 siRNA oligo Duplex | 101082104 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608225 | Pre-made Dog/Canine PIK3R6 siRNA oligo Duplex | 608225 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515621 | Pre-made Bovines/Cattle PIK3R6 siRNA oligo Duplex | 515621 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062779 | Pre-made Equine/Horse PIK3R6 siRNA oligo Duplex | 100062779 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PIK3R6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2242-Ab | Human | Anti-Human PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2242-Ab | Rat | Anti-Rat PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2242-Ab | Mouse | Anti-Mouse PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2242-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2242-Ab | Cat/Feline | Anti-Cat/Feline PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2242-Ab | Dog/Canine | Anti-Dog/Canine PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2242-Ab | Bovines/Cattle | Anti-Bovines/Cattle PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2242-Ab | Equine/Horse | Anti-Equine/Horse PIK3R6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PIK3R6 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2242-Ag | Human | Human PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2242-Ag | Rat | Rat PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2242-Ag | Mouse | Mouse PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2242-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2242-Ag | Cat/Feline | Cat/Feline PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2242-Ag | Dog/Canine | Dog/Canine PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2242-Ag | Bovines/Cattle | Bovines/Cattle PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2242-Ag | Equine/Horse | Equine/Horse PIK3R6 VLP (virus-like particle) | HEK293 | Products Developing |
