Explore OGT gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| Target ID |
GM-MP2223
|
| Target Name |
OGT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8473
|
| Gene ID |
100056148 (Equus caballus), 101094162 (Felis catus), 108155 (Mus musculus), 26295 (Rattus norvegicus)
480955 (Canis lupus familiaris), 532053 (Bos taurus), 698268 (Macaca mulatta), 8473 (Homo sapiens)
|
| Target Alternative Names |
1110038P24Rik,4831420N21Rik,HINCUT-1,HRNT1,MRX106,O-GLCNAC,O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit (OGT),OGT,OGT1,Ogt,Ogtl,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit,XLID106
|
| Uniprot Accession |
Q8CGY8,P56558,O15294
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Insulin resistance, Other types of O-glycan biosynthesis
|
| Gene Ensembl |
ENSECAG00000023721, ENSMUSG00000034160, ENSCAFG00845018937, ENSBTAG00000000902, ENSMMUG00000015238, ENSG00000147162
|
Pre-made viral vector of OGT cDNA Clones/ORF Plasmid
OGT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8473 | Pre-made Human OGT/OGT1/HRNT1 siRNA oligo Duplex | 8473 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26295 | Pre-made Rat Ogt siRNA oligo Duplex | 26295 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo108155 | Pre-made Mouse Ogt/Ogtl/1110038P24Rik siRNA oligo Duplex | 108155 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698268 | Pre-made Cynomolgus/Rhesus macaque OGT siRNA oligo Duplex | 698268 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094162 | Pre-made Cat/Feline OGT siRNA oligo Duplex | 101094162 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480955 | Pre-made Dog/Canine OGT siRNA oligo Duplex | 480955 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532053 | Pre-made Bovines/Cattle OGT siRNA oligo Duplex | 532053 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056148 | Pre-made Equine/Horse OGT siRNA oligo Duplex | 100056148 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OGT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2223-Ab | Human | Anti-Human OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2223-Ab | Rat | Anti-Rat OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2223-Ab | Mouse | Anti-Mouse OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2223-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2223-Ab | Cat/Feline | Anti-Cat/Feline OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2223-Ab | Dog/Canine | Anti-Dog/Canine OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2223-Ab | Bovines/Cattle | Anti-Bovines/Cattle OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2223-Ab | Equine/Horse | Anti-Equine/Horse OGT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
OGT VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2223-Ag | Human | Human OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2223-Ag | Rat | Rat OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2223-Ag | Mouse | Mouse OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2223-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2223-Ag | Cat/Feline | Cat/Feline OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2223-Ag | Dog/Canine | Dog/Canine OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2223-Ag | Bovines/Cattle | Bovines/Cattle OGT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2223-Ag | Equine/Horse | Equine/Horse OGT VLP (virus-like particle) | HEK293 | Products Developing |
