Explore NUMB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
| Target ID |
GM-MP2219
|
| Target Name |
NUMB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8650
|
| Gene ID |
100050235 (Equus caballus), 101087490 (Felis catus), 18222 (Mus musculus), 29419 (Rattus norvegicus)
480381 (Canis lupus familiaris), 512187 (Bos taurus), 696528 (Macaca mulatta), 8650 (Homo sapiens)
|
| Target Alternative Names |
C14orf41,NUMB,Nb,Numb,Protein S171,Protein numb homolog,S171,c14_5527,h-Numb
|
| Uniprot Accession |
Q9QZS3,Q2LC84,P49757
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000016684, ENSMUSG00000021224, ENSCAFG00845012636, ENSBTAG00000011683, ENSMMUG00000020196, ENSG00000133961
|
NUMB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8650 | Pre-made Human NUMB/S171/C14orf41 siRNA oligo Duplex | 8650 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29419 | Pre-made Rat Numb siRNA oligo Duplex | 29419 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18222 | Pre-made Mouse Numb/Nb siRNA oligo Duplex | 18222 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696528 | Pre-made Cynomolgus/Rhesus macaque NUMB siRNA oligo Duplex | 696528 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087490 | Pre-made Cat/Feline NUMB siRNA oligo Duplex | 101087490 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480381 | Pre-made Dog/Canine NUMB siRNA oligo Duplex | 480381 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512187 | Pre-made Bovines/Cattle NUMB siRNA oligo Duplex | 512187 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050235 | Pre-made Equine/Horse NUMB siRNA oligo Duplex | 100050235 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NUMB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2219-Ab | Human | Anti-Human NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2219-Ab | Rat | Anti-Rat NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2219-Ab | Mouse | Anti-Mouse NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2219-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2219-Ab | Cat/Feline | Anti-Cat/Feline NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2219-Ab | Dog/Canine | Anti-Dog/Canine NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2219-Ab | Bovines/Cattle | Anti-Bovines/Cattle NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2219-Ab | Equine/Horse | Anti-Equine/Horse NUMB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NUMB VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2219-Ag | Human | Human NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2219-Ag | Rat | Rat NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2219-Ag | Mouse | Mouse NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2219-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2219-Ag | Cat/Feline | Cat/Feline NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2219-Ag | Dog/Canine | Dog/Canine NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2219-Ag | Bovines/Cattle | Bovines/Cattle NUMB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2219-Ag | Equine/Horse | Equine/Horse NUMB VLP (virus-like particle) | HEK293 | Products Developing |
