Explore NCOA1/SRC-1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2212
|
| Target Name |
NCOA1/SRC-1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8648
|
| Gene ID |
100056042 (Equus caballus), 101094588 (Felis catus), 17977 (Mus musculus), 313929 (Rattus norvegicus)
475684 (Canis lupus familiaris), 525346 (Bos taurus), 718524 (Macaca mulatta), 8648 (Homo sapiens)
|
| Target Alternative Names |
Class E basic helix-loop-helix protein 74 (bHLHe74),F-SRC-1,KAT13A,NCOA1,NCoA-1,NRC-1,Ncoa1,Nuclear receptor coactivator 1,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,SRC-1,SRC-a,SRC1,Steroid receptor coactivator 1 (SRC-1),bHLHe42,bHLHe74,mNRC-1
|
| Uniprot Accession |
P70365,Q15788
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Thyroid hormone signaling pathway, Pathways in cancer, Breast cancer
|
| Gene Ensembl |
ENSECAG00000017819, ENSMUSG00000020647, ENSCAFG00845024663, ENSBTAG00000015007, ENSMMUG00000020838, ENSG00000084676
|
| Target Classification |
Tumor-associated antigen (TAA)
|
NCOA1/SRC-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8648 | Pre-made Human NCOA1/SRC1/KAT13A siRNA oligo Duplex | 8648 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313929 | Pre-made Rat Ncoa1/SRC-1 siRNA oligo Duplex | 313929 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17977 | Pre-made Mouse Ncoa1/SRC1/NRC-1 siRNA oligo Duplex | 17977 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718524 | Pre-made Cynomolgus/Rhesus macaque NCOA1 siRNA oligo Duplex | 718524 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094588 | Pre-made Cat/Feline NCOA1 siRNA oligo Duplex | 101094588 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475684 | Pre-made Dog/Canine NCOA1/SRC1 siRNA oligo Duplex | 475684 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525346 | Pre-made Bovines/Cattle NCOA1 siRNA oligo Duplex | 525346 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056042 | Pre-made Equine/Horse NCOA1 siRNA oligo Duplex | 100056042 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NCOA1/SRC-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2212-Ab | Human | Anti-Human NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2212-Ab | Rat | Anti-Rat NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2212-Ab | Mouse | Anti-Mouse NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2212-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2212-Ab | Cat/Feline | Anti-Cat/Feline NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2212-Ab | Dog/Canine | Anti-Dog/Canine NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2212-Ab | Bovines/Cattle | Anti-Bovines/Cattle NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2212-Ab | Equine/Horse | Anti-Equine/Horse NCOA1/SRC-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NCOA1/SRC-1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2212-Ag | Human | Human NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2212-Ag | Rat | Rat NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2212-Ag | Mouse | Mouse NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2212-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2212-Ag | Cat/Feline | Cat/Feline NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2212-Ag | Dog/Canine | Dog/Canine NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2212-Ag | Bovines/Cattle | Bovines/Cattle NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2212-Ag | Equine/Horse | Equine/Horse NCOA1/SRC-1 VLP (virus-like particle) | HEK293 | Products Developing |
