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Target
sublocation: Transmembrane Protein.
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2182
|
| Target Name |
L-Plastin/LCP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3936
|
| Gene ID |
100050663 (Equus caballus), 101081857 (Felis catus), 18826 (Mus musculus), 306071 (Rattus norvegicus) 3936 (Homo sapiens), 476921 (Canis lupus familiaris), 540990 (Bos taurus), 703429 (Macaca mulatta)
|
| Target Alternative Names |
CP64,D14Ertd310e,HEL-S-37,L-PLASTIN,L-Plastin,L-plastin,LC64P,LCP-1,LCP1,LPL,Lcp1,Lymphocyte cytosolic protein 1 (LCP-1),PLS2,Plastin-2,Pls2,plastin-2,pp65
|
| Uniprot Accession |
Q61233,P13796
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Prostate Cancer
|
| Gene Ensembl |
ENSECAG00000023009, ENSMUSG00000021998, ENSG00000136167, ENSCAFG00845008232, ENSBTAG00000007079, ENSMMUG00000017033
|
Pre-made viral vector of L-Plastin/LCP1 cDNA Clones/ORF Plasmid
L-Plastin/LCP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3936 | Pre-made Human LCP1/LPL/CP64 siRNA oligo Duplex | 3936 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306071 | Pre-made Rat Lcp1 siRNA oligo Duplex | 306071 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18826 | Pre-made Mouse Lcp1/Pls2/pp65 siRNA oligo Duplex | 18826 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703429 | Pre-made Cynomolgus/Rhesus macaque LCP1/plastin-2 siRNA oligo Duplex | 703429 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081857 | Pre-made Cat/Feline LCP1 siRNA oligo Duplex | 101081857 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476921 | Pre-made Dog/Canine LCP1 siRNA oligo Duplex | 476921 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540990 | Pre-made Bovines/Cattle LCP1 siRNA oligo Duplex | 540990 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050663 | Pre-made Equine/Horse LCP1 siRNA oligo Duplex | 100050663 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
L-Plastin/LCP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2182-Ab | Human | Anti-Human L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2182-Ab | Rat | Anti-Rat L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2182-Ab | Mouse | Anti-Mouse L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2182-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2182-Ab | Cat/Feline | Anti-Cat/Feline L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2182-Ab | Dog/Canine | Anti-Dog/Canine L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2182-Ab | Bovines/Cattle | Anti-Bovines/Cattle L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2182-Ab | Equine/Horse | Anti-Equine/Horse L-Plastin/LCP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
L-Plastin/LCP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2182-Ag | Human | Human L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2182-Ag | Rat | Rat L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2182-Ag | Mouse | Mouse L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2182-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2182-Ag | Cat/Feline | Cat/Feline L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2182-Ag | Dog/Canine | Dog/Canine L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2182-Ag | Bovines/Cattle | Bovines/Cattle L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2182-Ag | Equine/Horse | Equine/Horse L-Plastin/LCP1 VLP (virus-like particle) | HEK293 | Products Developing |