Explore IQGAP1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2166
|
| Target Name |
IQGAP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8826
|
| Gene ID |
100068724 (Equus caballus), 101087841 (Felis catus), 104968536 (Bos taurus), 29875 (Mus musculus) 361598 (Rattus norvegicus), 479050 (Canis lupus familiaris), 709283 (Macaca mulatta), 8826 (Homo sapiens)
|
| Target Alternative Names |
D7Ertd237e,D7Ertd257e,HUMORFA01,IQGAP1,Iqgap1,Ras GTPase-activating-like protein IQGAP1,SAR1,mKIAA0051,p195
|
| Uniprot Accession |
Q9JKF1,P46940
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Adherens junction, Regulation of actin cytoskeleton, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000023879, ENSBTAG00000013060, ENSMUSG00000030536, ENSMMUG00000011882, ENSG00000140575
|
IQGAP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8826 | Pre-made Human IQGAP1/SAR1/p195 siRNA oligo Duplex | 8826 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361598 | Pre-made Rat Iqgap1 siRNA oligo Duplex | 361598 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29875 | Pre-made Mouse Iqgap1/mKIAA0051/D7Ertd237e siRNA oligo Duplex | 29875 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709283 | Pre-made Cynomolgus/Rhesus macaque IQGAP1 siRNA oligo Duplex | 709283 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087841 | Pre-made Cat/Feline IQGAP1 siRNA oligo Duplex | 101087841 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479050 | Pre-made Dog/Canine IQGAP1 siRNA oligo Duplex | 479050 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo104968536 | Pre-made Bovines/Cattle IQGAP1 siRNA oligo Duplex | 104968536 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068724 | Pre-made Equine/Horse IQGAP1 siRNA oligo Duplex | 100068724 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IQGAP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2166-Ab | Human | Anti-Human IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2166-Ab | Rat | Anti-Rat IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2166-Ab | Mouse | Anti-Mouse IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2166-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2166-Ab | Cat/Feline | Anti-Cat/Feline IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2166-Ab | Dog/Canine | Anti-Dog/Canine IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2166-Ab | Bovines/Cattle | Anti-Bovines/Cattle IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2166-Ab | Equine/Horse | Anti-Equine/Horse IQGAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
IQGAP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2166-Ag | Human | Human IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2166-Ag | Rat | Rat IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2166-Ag | Mouse | Mouse IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2166-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2166-Ag | Cat/Feline | Cat/Feline IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2166-Ag | Dog/Canine | Dog/Canine IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2166-Ag | Bovines/Cattle | Bovines/Cattle IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2166-Ag | Equine/Horse | Equine/Horse IQGAP1 VLP (virus-like particle) | HEK293 | Products Developing |