Explore FRS2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Enables fibroblast growth factor receptor binding activity and neurotrophin TRKA receptor binding activity. Involved in negative regulation of cardiac muscle cell differentiation. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in adherens junction. Biomarker of renal cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-MP2132
|
| Target Name |
FRS2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10818
|
| Gene ID |
100052205 (Equus caballus), 101099133 (Felis catus), 10818 (Homo sapiens), 314850 (Rattus norvegicus)
327826 (Mus musculus), 474444 (Canis lupus familiaris), 538624 (Bos taurus), 717117 (Macaca mulatta)
|
| Target Alternative Names |
C330018A15Rik,FGFR substrate 2,FGFR-signaling adaptor SNT,FRS1A,FRS2,FRS2-alpha,FRS2A,FRS2alpha,Fibroblast growth factor receptor substrate 2,Frs2,Frs2alpha,SNT,SNT-1,SNT1,Suc1-associated neurotrophic factor target 1 (SNT-1)
|
| Uniprot Accession |
Q8WU20,Q8C180
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Neurotrophin signaling pathway, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000020194, ENSG00000166225, ENSMUSG00000020170, ENSCAFG00845017484, ENSBTAG00000019155, ENSMMUG00000010819
|
Pre-made viral vector of FRS2 cDNA Clones/ORF Plasmid
FRS2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10818 | Pre-made Human FRS2/SNT/SNT1 siRNA oligo Duplex | 10818 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo314850 | Pre-made Rat Frs2 siRNA oligo Duplex | 314850 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo327826 | Pre-made Mouse Frs2/SNT1/SNT-1 siRNA oligo Duplex | 327826 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717117 | Pre-made Cynomolgus/Rhesus macaque FRS2 siRNA oligo Duplex | 717117 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099133 | Pre-made Cat/Feline FRS2 siRNA oligo Duplex | 101099133 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474444 | Pre-made Dog/Canine FRS2 siRNA oligo Duplex | 474444 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538624 | Pre-made Bovines/Cattle FRS2 siRNA oligo Duplex | 538624 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052205 | Pre-made Equine/Horse FRS2 siRNA oligo Duplex | 100052205 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FRS2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2132-Ab | Human | Anti-Human FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP2132-Ab | Rat | Anti-Rat FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP2132-Ab | Mouse | Anti-Mouse FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP2132-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP2132-Ab | Cat/Feline | Anti-Cat/Feline FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP2132-Ab | Dog/Canine | Anti-Dog/Canine FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP2132-Ab | Bovines/Cattle | Anti-Bovines/Cattle FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP2132-Ab | Equine/Horse | Anti-Equine/Horse FRS2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
FRS2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2132-Ag | Human | Human FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2132-Ag | Rat | Rat FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2132-Ag | Mouse | Mouse FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2132-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2132-Ag | Cat/Feline | Cat/Feline FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2132-Ag | Dog/Canine | Dog/Canine FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2132-Ag | Bovines/Cattle | Bovines/Cattle FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2132-Ag | Equine/Horse | Equine/Horse FRS2 VLP (virus-like particle) | HEK293 | Products Developing |
