Explore FLNC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Mutations in this gene are a cause of cardiopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2022]
| Target ID |
GM-MP2127
|
| Target Name |
FLNC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2318
|
| Gene ID |
100071760 (Equus caballus), 101081210 (Felis catus), 2318 (Homo sapiens), 362332 (Rattus norvegicus)
482266 (Canis lupus familiaris), 528415 (Bos taurus), 68794 (Mus musculus), 700223 (Macaca mulatta)
|
| Target Alternative Names |
1110055E19Rik,ABP-280,ABP-280-like protein,ABP-L,ABP280A,ABPA,ABPL,ARVC15,Actin-binding-like protein,CMH26,FLN-C,FLN2,FLNC,FLNc,Filamin-2,Filamin-C,Fln2,Flnc,Gamma-filamin,MFM5,MPD4,RCM5
|
| Uniprot Accession |
Q14315,D3ZHA0,Q8VHX6
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Prostate Cancer, Mucocutaneous lymph node syndrome [Kawasaki]
|
| Disease from KEGG |
MAPK signaling pathway, Focal adhesion, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000010052, ENSG00000128591, ENSCAFG00845022554, ENSBTAG00000006253, ENSMUSG00000068699, ENSMMUG00000006296
|
FLNC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2318 | Pre-made Human FLNC/ABPA/ABPL siRNA oligo Duplex | 2318 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362332 | Pre-made Rat Flnc/ABP-L/FLN-C siRNA oligo Duplex | 362332 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo68794 | Pre-made Mouse Flnc/ABPL/Fln2 siRNA oligo Duplex | 68794 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700223 | Pre-made Cynomolgus/Rhesus macaque FLNC siRNA oligo Duplex | 700223 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081210 | Pre-made Cat/Feline FLNC siRNA oligo Duplex | 101081210 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482266 | Pre-made Dog/Canine FLNC siRNA oligo Duplex | 482266 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528415 | Pre-made Bovines/Cattle FLNC siRNA oligo Duplex | 528415 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071760 | Pre-made Equine/Horse FLNC siRNA oligo Duplex | 100071760 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FLNC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2127-Ab | Human | Anti-Human FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2127-Ab | Rat | Anti-Rat FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2127-Ab | Mouse | Anti-Mouse FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2127-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2127-Ab | Cat/Feline | Anti-Cat/Feline FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2127-Ab | Dog/Canine | Anti-Dog/Canine FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2127-Ab | Bovines/Cattle | Anti-Bovines/Cattle FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2127-Ab | Equine/Horse | Anti-Equine/Horse FLNC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
FLNC VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2127-Ag | Human | Human FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2127-Ag | Rat | Rat FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2127-Ag | Mouse | Mouse FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2127-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2127-Ag | Cat/Feline | Cat/Feline FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2127-Ag | Dog/Canine | Dog/Canine FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2127-Ag | Bovines/Cattle | Bovines/Cattle FLNC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2127-Ag | Equine/Horse | Equine/Horse FLNC VLP (virus-like particle) | HEK293 | Products Developing |
