Explore Filamin B/FLNB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
| Target ID |
GM-MP2126
|
| Target Name |
Filamin B/FLNB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2317
|
| Gene ID |
100057963 (Equus caballus), 101098612 (Felis catus), 2317 (Homo sapiens), 286940 (Mus musculus)
306204 (Rattus norvegicus), 484713 (Canis lupus familiaris), 613533 (Bos taurus), 702732 (Macaca mulatta)
|
| Target Alternative Names |
ABP-278,ABP-280,ABP-280 homolog,AOI,Actin-binding-like protein,Beta-filamin,FH1,FLN-B,FLN1L,FLNB,Filamin B,Filamin homolog 1 (Fh1),Filamin-3,Filamin-B,Fln-b,Flnb,LRS1,SCT,TABP,TAP,Thyroid autoantigen,Truncated actin-binding protein (Truncated ABP)
|
| Uniprot Accession |
O75369,Q80X90
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Mucocutaneous lymph node syndrome [Kawasaki]
|
| Disease from KEGG |
MAPK signaling pathway, Focal adhesion, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000015849, ENSG00000136068, ENSMUSG00000025278, ENSCAFG00845020721, ENSBTAG00000022004, ENSMMUG00000000706
|
Filamin B/FLNB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2317 | Pre-made Human FLNB/AOI/FH1 siRNA oligo Duplex | 2317 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306204 | Pre-made Rat Flnb siRNA oligo Duplex | 306204 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286940 | Pre-made Mouse Flnb/Fln-b siRNA oligo Duplex | 286940 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702732 | Pre-made Cynomolgus/Rhesus macaque FLNB siRNA oligo Duplex | 702732 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098612 | Pre-made Cat/Feline FLNB siRNA oligo Duplex | 101098612 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484713 | Pre-made Dog/Canine FLNB siRNA oligo Duplex | 484713 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613533 | Pre-made Bovines/Cattle FLNB siRNA oligo Duplex | 613533 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057963 | Pre-made Equine/Horse FLNB siRNA oligo Duplex | 100057963 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Filamin B/FLNB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2126-Ab | Human | Anti-Human Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2126-Ab | Rat | Anti-Rat Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2126-Ab | Mouse | Anti-Mouse Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2126-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2126-Ab | Cat/Feline | Anti-Cat/Feline Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2126-Ab | Dog/Canine | Anti-Dog/Canine Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2126-Ab | Bovines/Cattle | Anti-Bovines/Cattle Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2126-Ab | Equine/Horse | Anti-Equine/Horse Filamin B/FLNB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Filamin B/FLNB VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2126-Ag | Human | Human Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2126-Ag | Rat | Rat Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2126-Ag | Mouse | Mouse Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2126-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2126-Ag | Cat/Feline | Cat/Feline Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2126-Ag | Dog/Canine | Dog/Canine Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2126-Ag | Bovines/Cattle | Bovines/Cattle Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2126-Ag | Equine/Horse | Equine/Horse Filamin B/FLNB VLP (virus-like particle) | HEK293 | Products Developing |
